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Cayman Chemical Zardavern 10mg
SDP

Supplier:  Cayman Chemical 2968510 MG

Encompass_Preferred

A dual inhibitor of PDE3 and PDE4 (IC50s = 0.617 and 1.738 μM, respectively, for the rat cardiac ventricle enzymes); selective for PDE3 and PDE4 over PDE1B, PDE2, and PDE5 (IC50s = >138 μM for all); inhibits aggregation of human platelets induced by ADP, PAF, collagen, arachidonic acid, or PGE1 and ADP (IC50s = 1.5-16.2 μM); inhibits zymosan-induced superoxide anion release from human PMNs (IC50 = 0.4 μM); decreases lung resistance and increases dynamic compliance in a rat model of acetylcholine-induced bronchospasm at 10 μmol/kg; decreases the viability of HeLa, COLO 741, NCI H2122, and A2058 cells (IC50s = 0.032, 0.027, 0.26, and 0.13 μM, respectively)

Catalog No. 50-298-9764


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