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Medchemexpress LLC Zelavespib hydrochloride | 2095432-24-7 | 99.25% | 548.83 | 25 MG

Supplier: Medchemexpress LLC 25MGHY11038B
Zelavespib hydrochloride is a potent Hsp90 inhibitor primarily used for research. It demonstrates significant activity against various tumor cells, inducing apoptosis and inhibiting growth.
- Potent Hsp90 inhibitor with an IC50 of 51 nM in MDA-MB-468 cells.
- Inhibits growth of multiple tumor cell lines.
- Induces significant apoptosis in triple-negative breast cancers (TNBCs).
- Downregulates oncoproteins involved in the invasive potential of TNBCs.
- Cytotoxic to CLL cells with minimal effects on PBMC or resting B cells.
- Reduces CLL viability by inducing mitochondrial apoptosis.
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