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Medchemexpress LLC Zenidolol hydrochloride | 72795-01-8 | 99.7% | 313.86 | 1 ML
Supplier: Medchemexpress LLC HY1395110MM/1ML
Zenidolol hydrochloride (ICI-118551 hydrochloride) is a highly selective β2 adrenergic receptor antagonist. It exhibits Kis of 0.7, 49.5, and 611 nM for β2, β1, and β3 receptors, respectively, making it a potent research tool for studying adrenergic receptor activity.
- Inhibits cAMP accumulation with an IC50 of 1.7 μM in IMCD cells.
- Induces prominent vasorelaxation of norepinephrine pre-contracted PA.
- Significantly affects beat duration in failing human heart.
- Reduces systolic pressure in the pulmonary circuit in mice.
- Negative inotropic effect not cAMP-related.
- Available in solid, solution, or solid + solvent formats.
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