Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Assays
  5. Class-Specific Protein Assay Kits
  6. 22157393

ZeptoMetrix OXItek Glutathione Reductase Assay Kit
SDP

Catalog No. 22157393 Shop All ZeptoMetrix Corporation Products
Change view
Click to view available options
Quantity:
100 Tests
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
22-157-393 100 Tests
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 22-157-393 Supplier ZeptoMetrix Supplier No. 0805004
Only null left
Add to Cart
Add to Cart

Description

Includes

120mL of GR-assay buffer, 4 vials of GR-reagent 1, 4 vials of GR-reagent 2, 25mL of GR-reagent 3, 1 vial of QC material.

Provides an indirect and highly reproducible method of quantifying the activity of total cellular glutathione reductase

Glutathione reductase (GR, EC No. 1.6.4.2) is a flavoprotein that is required for the conversion of oxidized glutathione (GSSG) to reduced glutathione (GSH). At the same time, it oxidizes nicotinamide adenine dinucleotide phosphate (NADPH). This universally
present enzyme is essential for the maintenance of reduced glutathione (GSH) levels in vivo. Reduced glutathione plays an important role in oxidoreduction processes and detoxification of H2O2 and organic peroxides, which are substances produced in large quantities during inflammatory processes in living cells. Glutathione reductase therefore plays a major role in glutathione peroxidase (GPx) and glutathione stransferase (GST) reactions as an adjunct in the control of peroxides and free radicals.When levels of catalase, another universally present antioxidant enzyme, are decreased, the glutathione dependant enzymes become activated. A deficiency of glutathione reductase is characterized by hemolysis owing to the increased sensitivity of erythrocyte (RBC) membranes to H2O2 that lead to osmotic fragility. This reaction is thus required for the stability and integrity of red cells.

Specifications

Certifications/Compliance ISO 13485
Product Type OXItek Glutathione Reductase assay Kit
Sufficient For 100 Tests
For Use With (Application) For quantifying the activity of to tal cellular Glutathione Reductase
Kit Contents GPx reagent 2 4 vial/kit, GPx-assay buffer 120 mL/kit, GPx-reagent 1 4 vial/kit, Gpx-reagent 3 25 mL/kit, QC material 1 vial/kit
Quantity 100 Tests
Storage Requirements 2°C to 4°C

Research purposes only. Not for in vitro diagnostic use.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.