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Cayman Chemical ZIyuglycosIde I 10mg
SDP

Supplier:  Cayman Chemical 3732010 MG

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A stimulator of sGC stimulates the formation of cGMP in CHO cells expressing recombinant rat sGC in the absence and presence of SNAP (EC50s 1005 and 39 nM respectively) an effect that can be reversed by ODQ inhibits phenylephrine-induced contractions in isolated rabbit saphenous artery rings rabbit aortic rings and canine femoral vein rings (IC50s 798 692 and 3072 nM respectively) decreases the coronary perfusion pressure in isolated perfused rat hearts decreases proteinuria and increases survival in an (mRenR2)27 transgenic rat model of hypertension at 3 or 10 mg/kg

Catalog No. 50-291-7378


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