Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC ZLN024 hydrochloride | 1883548-91-1 | 98.5% | 361.69 | 1 ML
Supplier: Medchemexpress LLC HY16708A10MM/1ML
ZLN024 hydrochloride is an allosteric activator of AMPK, directly stimulating active AMPK heterotrimers as well as inactive α1 subunit truncations. This activation requires pre-phosphorylation of Thr-172 by upstream kinases and protects AMPK Thr-172 from dephosphorylation. It activates AMPK in L6 myotubes, promoting glucose uptake and fatty acid oxidation without altering the ADP/ATP ratio. In vivo studies showed improved glucose tolerance and reduced fasting blood glucose in C57BKS db/db mice.
- Allosterically stimulates active AMPK heterotrimers.
- Activates AMPK in L6 myotubes.
- Stimulates glucose uptake and fatty acid oxidation.
- Improves glucose tolerance.
- Reduces fasting blood glucose.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?