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Medchemexpress LLC ZLN024 hydrochloride | 1883548-91-1 | 98.5% | 361.69 | 1 ML
SDP

Catalog No. 5000393674
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ZLN024 hydrochloride is an allosteric activator of AMPK, directly stimulating active AMPK heterotrimers as well as inactive α1 subunit truncations. This activation requires pre-phosphorylation of Thr-172 by upstream kinases and protects AMPK Thr-172 from dephosphorylation. It activates AMPK in L6 myotubes, promoting glucose uptake and fatty acid oxidation without altering the ADP/ATP ratio. In vivo studies showed improved glucose tolerance and reduced fasting blood glucose in C57BKS db/db mice.

  • Allosterically stimulates active AMPK heterotrimers.
  • Activates AMPK in L6 myotubes.
  • Stimulates glucose uptake and fatty acid oxidation.
  • Improves glucose tolerance.
  • Reduces fasting blood glucose.

Catalog No. 50-003-93674 Supplier Medchemexpress LLC Supplier No. HY16708A10MM/1ML
May include imposed supplier surcharges.
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ZLN024 hydrochloride is an allosteric activator of AMPK, directly stimulating active AMPK heterotrimers as well as inactive α1 subunit truncations. This activation requires pre-phosphorylation of Thr-172 by upstream kinases and protects AMPK Thr-172 from dephosphorylation. It activates AMPK in L6 myotubes, promoting glucose uptake and fatty acid oxidation without altering the ADP/ATP ratio. In vivo studies showed improved glucose tolerance and reduced fasting blood glucose in C57BKS db/db mice.

  • Allosterically stimulates active AMPK heterotrimers.
  • Activates AMPK in L6 myotubes.
  • Stimulates glucose uptake and fatty acid oxidation.
  • Improves glucose tolerance.
  • Reduces fasting blood glucose.

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