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Medchemexpress LLC Zm323881 (hydrochloride) | 193000-39-4 | C22H19ClFN3O2 | 50 MG

Supplier: Medchemexpress LLC HY15467A50MG
ZM323881 hydrochloride is a potent and selective VEGFR2 inhibitor with an IC50 of less than 2 nM. It is an anilinoquinazoline that potently inhibits VEGFR2 (KDR) tyrosine kinase activity, demonstrating excellent selectivity versus other receptor tyrosine kinases. It inhibits VEGF-A-induced endothelial cell proliferation (IC50=8 nM) and VEGFR2 tyrosine phosphorylation, making it suitable for research applications.
- Potent and selective VEGFR2 inhibitor
- Anilinoquinazoline structure
- Inhibits VEGF-A-induced endothelial cell proliferation
- Inhibits VEGFR2 tyrosine phosphorylation
- For research use only
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