Cayman Chemical zngbs zoma cns 8Sogaol 10mg

Supplier:  Cayman Chemical 4027310 MG

A polyphenol with diverse biological activities; inhibits TAK1 (IC50 = 5.027 nM); inhibits COX-2 (IC50 = 32 µM); reduces IL-17-induced secretion of IL-8 from SW 982 sarcoma cells and Tnf-α from RAW 264.7 macrophages at 10 µM; decreases TNF-α-induced secretion of IL-6, IL-8, and CCL2 by, and reduces IL-17-induced migration and invasion of, primary human rheumatoid arthritis fibroblast-like synoviocytes at 5 or 10 µM; inhibits PMA-induced migration and invasion of MDA-MB-231 cancer cells at 10 µM; reduces paw thickness, as well as adjuvant-induced increases in joint space, synovial tissue proliferation, and cartilage damage, and improves gait without reducing body weight in a rat model of AIA at 30 mg/kg every three days

Catalog No. 50-294-5695