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Echelon Biosciences Research Labs ZSTK474 PI3K INHIBITOR 100mg
SDP

Supplier:  Echelon Biosciences Research Labs B0307100MG

Encompass

ZSTK474 is a potent inhibitor of all four isoforms of class I PI 3-kinase ( 6.7 nM, 10.4 nM, 11.7 nM, 1.8 nM). It binds to the ATP-binding pocket and is more active and less toxic than LY294002. ZSTK474 shows anti-tumor activity against human xenografts (A549, PC-3, WiDr) in mice by arresting cell growth. In addition, it was able to inhibit osteoclast formation and collagen-induced arthritis in a mouse model. This item is non returnable

Catalog No. 50-822-55


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