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Medchemexpress LLC ZT-1a | 212135-62-1 | 99.8% | 445.73 | 250 MG
SDP

Supplier:  Medchemexpress LLC 250MGHY136532

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ZT-1a is a potent, non-ATP-competitive, and selective SPAK inhibitor. It inhibits SPAK activity and decreases SPS1-related proline/alanine-rich kinase (SPAK)-dependent phosphorylation, thereby inhibiting Na-K-2Cl cotransporter (NKCC1) and stimulating K-Cl cotransporters (KCCs).

  • Potent, non-ATP-competitive, and selective SPAK inhibitor
  • Inhibits Na-K-2Cl cotransporter (NKCC1) activity
  • Stimulates K-Cl cotransporters (KCCs) activity
  • Inhibits SPAK-dependent cation-Cl cotransporters (CCC) phosphorylation in vivo

Catalog No. 50-003-49374


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