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Bachem Z-Val-Ala-DL-Asp-fluoromethylketone
SDP

Supplier:  Bachem 4026865.0025

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Z-Val-Ala-DL-Asp-fluoromethylketone, 220644-02-0, C21H28FN3O7, Mr 453.47, 25mg. Z-VAD-FMK. zVAD-FMK inhibited apoptosis induced by diverse stimuli. Preincubation of cells with this caspase-1 (ICE) inhibitor (50 uM) almost completely inhibited the formation of large kilobase-pair fragments of DNA, a characteristic biochemical change associated with apoptosis. Z-VAD-FMK was shown to irreversibly inhibit most types of caspases, hence it is also called pan-caspase inhibitor. For a cell-permeable analog see N-1560. Inhibitor of peptide:N-glycanase (PNGase).

Catalog No. 50-194-6683


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