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Zymo Research Corporation Zymo-Seq RRBS Library Kit (24 preps)
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Supplier:  Zymo Research Corporation D5460

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DNA methylation occurs predominantly in CpG contexts, and these CpG dinucleotides are more abundant in select regions of the genome. By enriching for CpG-dense regions and sequencing only the fragments pertaining to those regions, the RRBS platform allows for the capture of a significant amount of methylation data while reducing the amount of sequencing, leading to a substantially decreased cost. This combination makes RRBS the perfect platform for pilot studies. Libraries prepared by Zymo-Seq RRBS™ Library Kit cover 75% CpG islands, 70% gene promoters, 75% gene bodies, and 2.5-4 million unique CpG sites at 5-10x coverage when applied to human samples.

Catalog No. 50-195-7605


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