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Medchemexpress LLC Zzw-115 hydrochloride | 10122-45-9 | 98.1 % | 573.97 | 5 MG
Supplier: Medchemexpress LLC 5MGHY111838A
ZZW-115 hydrochloride is a potent NUPR1 inhibitor with a Kd of 2.1 μM. It induces tumor cell death through necroptosis and apoptosis, demonstrating anticancer activity. It is efficient in killing various cancer cells with IC50 values ranging from 0.42 μM to 4.93 μM. This compound also induces a decrease in ATP production and a ROS overproduction.
- Efficient in killing cancer cells with IC50 values ranging from 0.42 μM to 7.75 μM
- Induces tumor cell death via necroptosis and apoptosis
- Decreases ATP production and induces ROS overproduction
- Inhibits the growth of pancreatic xenografted tumors in vivo
- Demonstrates potent anticancer activity
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