This peptide also known as INS is the 15-23 fragment of the insulin beta chain recognized by islet-associated T cells. It was used in diabetes studies to assay the IFN-beta and IL-17 production by diabetogenic CD4 or CD8 T cells. This peptide stains the INS-reactive CTL clone, but doesn?t stain the splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice.ONE-LETTER SEQUENCE: LYLVCGERGMOLECULAR FORMULA: C44H72N12O13S1MOLECULAR WEIGHT:1009.19STORAGE CONDITIONS: -20 5CRESEARCH AREA: GastrointestinalREFERENCES: Hu, C. et al. J. Clin. Invest. 117, 3857 (2007); Amrani, A. et al. Nature 406, 739 (2000)