Cayman Chemical ImIdacloprId 25mg
An NMDA receptor antagonist (Ki 0.14 UM) binds to NMDA receptors containing GluN2A GluN2B GluN2C and GluN2D subunits (Kis 0.04 0.3 0.6 and 2 UM respectively) inhibits NMDA-induced depolarizations in isolated hemisected frog spinal cord (pA2 6.56) and NMDA-induced sodium efflux from rat brain slices (pA2 6.2) inhibits the clonic phase of sound-induced seizures in DBA/2 mice (ED50 65.8 Umol/kg) and the myoclonic phase of stroboscopic-induced seizures in P. papio photosensitive baboons (ED50 127 Umol/kg)