Nucleosides and Analogues
Medchemexpress LLC Flavin adenine dinucleotide disodium salt | 84366-81-4 | 99.7% | 500 MG
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor and a prosthetic group of a protein. It is involved in several important enzymatic reactions in metabolism.
- Endogenous metabolite
- Redox cofactor
- Prosthetic group of a protein
- Involved in several enzymatic reactions in metabolism
- Appearance: solid
- Color: yellow to orange
- Molecular weight: 829.51
- Formula: C27H31N9Na2O15P2
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 25 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. It exhibits anti-tumor activity and has been shown to inhibit tumor growth in vivo.
- Orally active A2a/A2b adenosine receptor antagonist
- Potent inhibition: IC50s of 1 nM (A2a) and 3 nM (A2b)
- Exhibits anti-tumor activity
- Inhibits tumor growth in female C57BL/6 mice
- Molecular weight: 444.46
Medchemexpress LLC Adenosine | 58-61-7 | MFCD00005752 | 100.0% | 1 ML
Adenosine is a ubiquitous, BBB-permeable endogenous autacoid that modulates various cellular physiological processes. It acts through four G protein-coupled receptors (A1, A2A, A2B, and A3) to influence neuronal activity, vascular function, platelet aggregation, and blood cell regulation. This ribonucleoside consists of adenine attached to a ribofuranose moiety.
- Acts through four G protein-coupled receptors (A1, A2A, A2B, A3).
- Modulates neuronal activity, vascular function, and blood cell regulation.
- Functions as an analgesic, vasodilator, and anti-arrhythmia agent.
- Induces apoptosis in various cancer cells.
- Promotes autophagy in HepG2 cells.
- High purity: 99.96%.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5'-triphosphate disodium salt hydrate Grade II, >=97% (HPLC), crystalline, from microbial | 34369-07-8 | MFCD00150755 | 1G
Adenosine 5'-triphosphate disodium salt hydrate Grade II, >=97% (HPLC), crystalline, from microbial | Purity: >=97% (HPLC) | 34369-07-8 | MFCD00150755 | 1G
Sigma Aldrich Fine Chemicals Biosciences Nicotinic acid adenine dinucleotide phosphate sodium salt >=92.5% | 5502-96-5 | MFCD00274064 | 10MG
Nicotinic acid adenine dinucleotide phosphate sodium salt >=92.5% | Purity: >=92.5% | 5502-96-5 | MFCD00274064 | 10MG
Sigma Aldrich Fine Chemicals Biosciences 5-Iodo-2'-deoxyuridine >=99% (HPLC) | 54-42-2 | MFCD00134656 | 25G
5-Iodo-2'-deoxyuridine >=99% (HPLC) | Purity: >=99% (HPLC) | Mol Wt: 354.1 | 54-42-2 | MFCD00134656 | 25G
Apexbio Technology LLC NAD+ 53-84-9 10mM (in 1mL H2O)
Nicotinamide adenine dinucleotide (NAD CAS number 53-84-9) is a coenzyme involved in oxidation-reduction reactions accepting electrons to form NADH Additionally NAD functions as a substrate in enzymatic processes mediated by poly(ADP-ribose) polymerases sirtuins and cyclic ADP-ribose synthases NAD analogs demonstrate inhibitory activity against CD38-associated NAD glycohydrolase (NADase) with reported IC50 values ranging from 2 mM to 10 mM In biomedical research NAD supplementation is investigated for addressing fatigue and fatigue-associated disorders
Research Products International Corp 5-Bromo-2'-Deoxyuridine, 5 Grams
Thymidine analog used for study of DNA synthesis. This analog selectively incorporates into cellular DNA during S-phase. Supplied as white powder.
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 50ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES URIDINE 5 -DIPHOSPHOGL 500MG
NC2945880 URIDINE 5 -DIPHOSPHOGL 500MG
Medchemexpress LLC Adenosine monophosphate-13C10 (dilithium) | 13C10H12Li2N5O7P | 1 MG
Adenosine monophosphate-13C10 (dilithium) | 13C10H12Li2N5O7P | 1 MG
Medchemexpress LLC ATP-polyamine-biotin | 1800401-93-7 | 98.06% | 50 MG
ATP-polyamine-biotin is the first cell-permeable ATP analogue, designed to function as an efficient kinase cosubstrate. It facilitates the biotin labeling of kinase substrates directly within live cells. This innovative compound allows for in vitro biotinylation experiments where the presence of the kinase, ATP-polyamine-biotin, and substrate leads to successful labeling, which is inhibited by kinase inhibitors or cleavage of the phosphoramidate bond.
- Promotes biotin labeling of kinase substrates in live cells.
- Functions as an efficient kinase cosubstrate.
- Observes biotinylation only in the presence of kinase.
- Inhibited by kinase inhibitors like staurosporine.
- Sensitive to acid incubation due to phosphoramidate bond cleavage.