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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with an EC50 of 4 nM. It is intended for research and analytical applications, and an analytical standard is also available.
Potent, selective, and orally bioavailable FXR agonist
Used in autophagy, metabolic disease, and cancer research
Consistent with structure via 1H NMR and MS
High purity of 99.8%
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Azido-PEG3-C6-Cl is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, capable of undergoing both copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
PEG-based PROTAC linker
Used in PROTAC synthesis
Click chemistry reagent
Contains an azide group
Participates in CuAAc reactions with alkyne groups
Undergoes SPAAC reactions with DBCO or BCN groups
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Zinc gluconate is the gluconate salt of zinc used as a research reagent in studies of inflammation, immune function, and nutritional supplementation. It is water- and DMSO-soluble, and manufacturer documentation reports a molecular weight of 455.67 and a typical purity of 98.0%.
Used in research of inflammation, zinc deficiency, and immune responses.
Soluble in DMSO and water at up to 50 mg/mL with ultrasonic assistance.
Molecular weight 455.67.
Purity 98.0% as supplied.
Storage: sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
In vivo formulation guidance provided for achieving ≥2.5 mg/mL in mixed solvent systems.
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BM-PEG3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) comprise two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These chimeras leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
Functions as a PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Features two distinct ligands connected by a linker
Ligands target an E3 ubiquitin ligase and a target protein
Employs the intracellular ubiquitin-proteasome system
Designed for selective degradation of target proteins
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Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide-based cereblon ligand and a linker used in PROTAC technology.
Synthesized E3 ligase ligand-linker conjugate
Incorporates Pomalidomide-based cereblon ligand
Used in PROTAC technology
Targets Cereblon
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Contains two different ligands connected by a linker
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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Chlorophyllin sodium copper salt is an orally active green pigment, antioxidant, and antimutagenic agent. It promotes hematopoiesis and thrombopoiesis.
Orally active green pigment
Antioxidant
Antimutagenic agent
Promotes hematopoiesis and thrombopoiesis
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