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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Click chemistry reagent containing an azide group
Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Tri(Amino-PEG4-amide)-amine is a PEG-based PROTAC linker, integral for the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are designed with two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the desired protein. This mechanism leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Peg-based protac linker
Used in the synthesis of protacs
Enables selective degradation of target proteins
Exploits the intracellular ubiquitin-proteasome system
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TCO-PEG3-NH2 is a click-chemistry reagent composed of a trans-cyclooctene (TCO) group linked to a three-unit polyethylene glycol spacer terminating in a primary amine. It enables fast bioorthogonal inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine-functionalized partners and amine-mediated conjugation for site-specific labeling of biomolecules.
Enables rapid iEDDA bioorthogonal chemistry for fast conjugation.
Terminal primary amine allows amide bond formation with carboxyl groups.
Three-unit PEG spacer improves aqueous solubility and reduces steric hindrance.
Suitable for site-specific labeling and bioconjugation workflows.
Typically supplied as a small solid quantity for laboratory use.
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Bis(1-chloro-2-propyl) phosphate is an organophosphate research chemical and a metabolite reference standard used in studies of organophosphate flame retardants and their metabolites. It is supplied as a small laboratory quantity for analytical and toxicological research.
Chemical identifiers: CAS 789440-10-4; formula C6H13Cl2O4P; molecular weight 251.04 g/mol.
Used as an analytical standard for metabolite identification and biomonitoring studies.
Provided as a 1 mg laboratory sample suitable for analytical assays and method development.
Intended for laboratory research use; consult the safety data sheet for handling and hazard information.
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Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases. It works by inhibiting the process by which cells synthesize DNA. This product is for research use only and not sold to patients.
Affects cell growth and division
Commonly used to fight certain diseases, especially cancer and autoimmune diseases
Works by inhibiting the process by which cells synthesize DNA
Biochemical reagent for life science related research
Can be used as a biological material or organic compound
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