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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Epidermal growth factor receptor 994-1002 acetyl amide is a peptide fragment derived from the epidermal growth factor receptor (EGFR) acetylated and amidated at its termini It is designed to serve as a tool for investigating receptor-ligand interactions and receptor activation mechanisms associated with EGFR-mediated signaling pathways Epidermal growth factor receptor 994-1002 acetyl amide acts by enabling the study of EGFR activation particularly receptor dimerization and autophosphorylation processes Based on its biological characteristics this peptide has research potential in evaluating therapeutic strategies targeting EGFR-mediated oncogenesis including studies of proliferation differentiation migration and survival in malignancies such as glioblastoma and lung cancers
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Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3) corresponds to a C-terminal segment of the EGFR protein involved in receptor autophosphorylation EGFR a transmembrane receptor tyrosine kinase undergoes activation upon ligand binding triggering receptor dimerization and subsequent phosphorylation of specific tyrosine residues within its C-terminus including the 985-996 region This phosphorylation facilitates recruitment of SH2 domain-containing signaling proteins thereby initiating pathways such as MAPK Akt and JNK which regulate cell proliferation migration and adhesion This peptide serves as a useful research tool for elucidating EGFR-mediated signaling and studying kinase-substrate interactions in cellular models
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Azido-PEG3-C6-Cl is a PEG-based linker bearing an azide group used for click chemistry and PROTAC synthesis. It facilitates conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), providing a versatile building block for bioconjugation and linker design.
Contains an azide functional group for efficient CuAAC reactions.
Compatible with strain-promoted azide-alkyne cycloaddition for catalyst-free conjugation.
PEG3 spacer improves solubility and provides linker flexibility.
Terminal chlorohexyl enables further chemical modification.
High purity and characterized molecular data support synthetic use.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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Oxypeucedanin hydrate is a natural product isolated from *D. anethifolia* and classified as a phenylpropanoid and coumarin. This laboratory chemical is used in the manufacture of substances and exhibits mild toxicity on fibroblasts and parental lymphoma cells.
Natural product
Isolated from *D. anethifolia*
Classified as a phenylpropanoid and coumarin
Exhibits mild toxicity on fibroblasts and parental lymphoma cells
Molecular weight: 304.29
Formula: C16H16O6
Appearance: Solid
Color: Off-white to light yellow
Storage as powder: -20°C for 3 years, 4°C for 2 years
Storage in solvent: -80°C for 6 months, -20°C for 1 month
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BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Purity: 99.94%
Molecular weight: 368.47
Chemical formula: C19H32N2O5
CAS number: 1841134-72-2
Appearance: Colorless to light yellow liquid
Density: 1.14±0.1 g/cm3
Used in PROTAC synthesis
Contains a BCN group for SPAAC reactions
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