Glycosyl compounds
Sigma Aldrich Fine Chemicals Biosciences Thiocolchicoside for system suitability European Pharmacopoeia (EP) Reference Standard | 602-41-5 | MFCD07995056 |
Thiocolchicoside for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 563.62 | 602-41-5 | MFCD07995056 |
Apexbio Technology LLC Beta-Lapachone 4707-32-8 10mM (in 1mL DMSO)
Beta-Lapachone (CAS 4707-32-8) is a small molecule inhibitor of DNA topoisomerase I In DNA unwinding assays beta-Lapachone suppresses topoisomerase I-mediated DNA relaxation at concentrations as low as 1 M without inhibiting topoisomerase II or inducing topoisomerase I-dependent DNA cleavage It exhibits broad cytotoxicity against human cancer cell lines such as AD2780s HT-29 DLD G480 and MCF-7 with IC50 values ranging from 2 to 5 M The compound induces cell death through cytochrome c release triggering both apoptosis and necrosis and affects cell cycle progression causing S-phase and G2/M arrest in different carcinoma cell models Beta-Lapachone is widely utilized in studies investigating topoisomerase I inhibition cancer cell cytotoxicity and cell cycle regulation
![eMolecules 7693-46-1 | 4-Nitrophenyl chloroformate | Oakwood Chemicals | MFCD00007321 | 201.560 | C7H4ClNO4 | 99.000 | [O-][N+](=O)c1ccc(OC(Cl)=O)cc1 | 100g | 480127710](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169149.jpg-250.jpg)
eMolecules 7693-46-1 | 4-Nitrophenyl chloroformate | Oakwood Chemicals | MFCD00007321 | 201.560 | C7H4ClNO4 | 99.000 | [O-][N+](=O)c1ccc(OC(Cl)=O)cc1 | 100g | 480127710
4-Nitrophenyl chloroformate | Oakwood Chemicals | 7693-46-1 | MFCD00007321 | 201.560 | C7H4ClNO4 | 99.000 | [O-][N+](=O)c1ccc(OC(Cl)=O)cc1 | 100g | 480127710
Medchemexpress LLC IKB beta/NFKBIB Hum 5ug | 5ug
IKB beta/NFKBIB protein effectively inhibits NF-kappa-B and prevents NF-kappa-B activation by forming a cytoplasmic complex After cell stimulation the non-phosphorylated form is resynthesized binds to NF-kappa-B aids nuclear transport and protects NF-kappa-B from NFKBIA-dependent inactivation IKB beta/NFKBIB Protein Human (His) is the recombinant human-derived IKB beta/NFKBIB protein expressed by E coli with N-6 His labeled tag
Medchemexpress LLC IKK alpha + IKK beta Antibody (YA349) | Protein A affinity purified | Predicted band size: 87 kDa; Observed band size: 87 kDa | 100UL
IKK alpha + IKK beta Antibody (YA349) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting IKK alpha + IKK beta. IKKβ protein, a serine kinase, plays a pivotal role in the NF-kappa-B signaling pathway, activated by diverse stimuli such as inflammatory cytokines, bacterial or viral products, DNA damage, or cellular stresses. As a constituent of the canonical IKK complex, IKKβ contributes to the conventional NF-kappa-B activation pathway.
- Suitable for Western blot (1:500-1:1000)
- Suitable for immunocytochemistry/immunofluorescence (1:100-1:500)
- Suitable for immunoprecipitation (assay dependent concentration)
- Targets inhibitors of NF-kappa-B for degradation
- Enables free NF-kappa-B nuclear translocation and gene activation
- Phosphorylates various signaling pathway components
- Influences diverse cellular processes and responses
Medchemexpress LLC Beta Amyloid 1-40 Antibody (YA3554) | 100 UL
Beta Amyloid 1-40 Antibody (YA3554) is a rabbit-derived IgG monoclonal antibody targeting beta Amyloid 1-40. It functions as a cell surface receptor on neurons, playing roles in neurite growth, neuronal adhesion, and axonogenesis, and participates in cell mobility and transcription regulation.
- Rabbit-derived, non-conjugated IgG monoclonal antibody
- Targets beta Amyloid 1-40
- Reactivity: human, mouse
- Formulation: PBS (pH 7.4), 0.1% BSA, 40% glycerol, 0.05% sodium azide
- Storage: -20°C for 1 year, avoid freeze/thaw cycles
- Appearance: liquid
- Shipping: blue ice
- Applications: WB (1:1000), IHC-P (1:1000), IF-Tissue (1:200)
Alkali Scientific 4 Nitrophenyl Phenylphosphonate, 1 G
4-Nitrophenyl Phenylphosphonate, 1g, is a reagent used in biochemical assays to study phosphatase and phosphodiesterase activity. The compound contains a phenylphosphonate group, which is cleaved by enzymes, releasing p-nitrophenyl, a yellow compound, indicating enzyme activity. This reagent is commonly used in enzyme kinetics studies and research related to enzyme-substrate interactions. The 1g quantity is sufficient for several small-scale experiments, providing a convenient amount for routine use in enzymology research. It is an essential tool for studying the action of phosphatases, phosphodiesterases, and other related enzymes, particularly in biochemical and molecular biology applications.
Alkali Scientific p Nitrophenyl β D fucopyranoside, 250 Mg
p Nitrophenyl β-D fucopyranoside (250 mg) is a highly effective substrate for studying fucosidase activity in biochemical assays. This reagent is commonly used in research related to carbohydrate enzymes and glycosidases, particularly in the breakdown of fucosidic linkages in glycoproteins and glycolipids. The compound releases a yellow color upon enzymatic hydrolysis, making it ideal for colorimetric analysis. Its application is especially useful in assays that require the measurement of fucosidase activity, aiding in research focused on glycosylation, enzyme kinetics, and the role of fucose in biological systems such as cell signaling and immunity.
Alkali Scientific p Nitrophenyl α D galactopyranoside, 50 Grams
Nitrophenyl alpha-D-galactopyranoside (50 g) is a chromogenic substrate used in enzyme assays to detect the presence of galactosidase activity. The substrate is hydrolyzed by enzymes to release a colored product, which can be visually observed or quantitatively measured. This reagent is ideal for studying enzyme activity in biological and biochemical research, including gene expression and metabolic pathways. It is commonly used in clinical diagnostics, microbiological testing, and environmental applications where detecting galactosidase activity is essential. The 50 g formulation provides a sufficient quantity for large-scale assays, ensuring reliable and consistent results in routine testing and research applications.
Cayman Chemical Derythro Lysosphingomyelin d
A bioactive sphingolipid; agonist of S1P1, S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors); agonist of ORG1 that induces calcium accumulation in cells overexpressing OGR1 (EC50 = ~35 nM); levels are increased in skin isolated from patients with atopic dermatitis, as well as postmortem brain from patients with Niemann-Pick disease type A
Medchemexpress LLC PDGF R beta Rat HE 100ug
PDGF R beta Protein a receptor tyrosine kinase binds ligands PDGFA PDGFB and PDGFD forming homodimers or heterodimers Ligand binding activates diverse signaling cascades in PDGF R beta with responses contingent on the specific ligand The modulation of responses involves heterodimer formation with another receptor PDGFRB PDGF R beta Protein Rat (HEK293 His) is the recombinant rat-derived PDGF R beta protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC 3-O-methyl-D-glucopyranose | 13224-94-7 | MFCD00063266 | 99.9% | 194.18 g/mol | C7H14O6 | 5 G
3-O-Methyl-D-glucopyranose is a biochemical reagent used in life-science research as a non-metabolizable glucose analog for studies of glucose transport and intracellular uptake. Supplied as a white to off-white powder intended for laboratory research use only.
- High purity: 99.9%.
- Non-metabolizable glucose analog for transport studies.
- White to off-white solid, suitable for assay preparation.
- Molecular weight 194.18 g/mol and CAS number 13224-94-7 for unambiguous identification.
- Stable under recommended storage conditions to preserve integrity.