Monosaccharides
Medchemexpress LLC Fludarabine (phosphate) | 75607-67-9 | 99.8% | 365.21 | 10 MG
Fludarabine phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. This product is for research use only.
- Mimics natural building blocks of DNA
- Interferes with normal DNA synthesis
- Inhibits DNA synthesis
- Shows anticancer activity against various human cell lines
- Significantly reduces cell viability in a dose-dependent manner in vitro
- Leads to complete regressions of tumors and cures in mice in vivo
Medchemexpress LLC Cuda disodium | 98.0% | 386.48 g/mol | C19H36N2Na2O3 | 5 MG
CUDA disodium is a potent, research-use small molecule inhibitor of soluble epoxide hydrolase (sEH) that modulates PPARα activity. Reported IC50 values are 11.1 nM (mouse sEH) and 112 nM (human sEH). Supplied as a 5 mg sample with 98.0% purity, it is intended for biochemical and pharmacological research in lipid metabolism and cardiovascular disease models.
- Potent sEH inhibition with reported IC50s of 11.1 nM (mouse) and 112 nM (human).
- Enhances peroxisome proliferator-activated receptor alpha activity in cellular models.
- High purity (98.0%) suitable for biochemical assays.
- Small quantity packaging (5 mg) for screening and early-stage studies.
- Storage recommendations provided for stability in solvent and dry conditions.
Medchemexpress LLC Sitagliptin phosphate monohydrate | 654671-77-9 | 99.8% | 523.32 | 1 ML
Sitagliptin phosphate monohydrate, also known as MK-0431, is an orally active and highly selective DPP4 inhibitor. It works by blocking the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), thereby increasing active incretin levels. This compound can also directly stimulate GLP-1 secretion by intestinal L cells through activation of the cAMP/PKA and ERK1/2 pathways, independently of DPP-4. It exhibits protective effects on pancreatic islet grafts in type 1 diabetes models and is used for studying both type 1 and type 2 diabetes.
- Orally active and highly selective DPP4 inhibitor.
- Blocks degradation of GLP-1 and GIP.
- Increases active incretin levels.
- Directly stimulates GLP-1 secretion.
- Protective effects on pancreatic islet grafts.
- Used for studying type 1 and type 2 diabetes.
TARGETMOL CHEMICALS INC GDP-L-fucose 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. GDP-L-fucose is a nucleotide sugar widely found in fungi and plants, playing a role in both the slave and secondary remedial metabolic pathways. Purity 98.06%
Medchemexpress LLC α-D-Glucose-1-phosphate disodium (Standard) | 56401-20-8 | 99.9% | 10 MG
α-D-Glucose-1-phosphate disodium (Standard) is the analytical standard of α-D-Glucose-1-phosphate disodium, intended for research and analytical applications. It serves as a starting material for glucuronic acid synthesis and finds use as a cytostatic compound, an antibiotic, an immunosuppressive agent, and a circulatory system therapy element.
- Used as a starting material for the synthesis of glucuronic acid.
- Can be used as a cytostatic compound essential for cardiopathic therapy.
- Can be used as an antibiotic.
- Can be used as an immunosuppressive agent.
- Can be used as a circulatory system therapy element.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC Palbociclib monohydrochloride | 827022-32-2 | 99.98% | C24H30ClN7O2 | 2 G
Palbociclib monohydrochloride (PD 0332991) is an orally active, selective inhibitor of CDK4 and CDK6. It demonstrates potent anti-proliferative activity and induces cell cycle arrest in cancer cells. This compound is utilized in research for HR-positive and HER2-negative breast cancer, as well as hepatocellular carcinoma.
- Orally active, selective inhibitor of CDK4 and CDK6.
- Demonstrates potent anti-proliferative activity.
- Induces cell cycle arrest in cancer cells.
- Utilized in research for HR-positive and HER2-negative breast cancer.
- Used in research for hepatocellular carcinoma.
Medchemexpress LLC Allitol (Allodulcitol) | 488-44-8 | 5 MG
Allitol (Allodulcitol) is an orally active rare sugar alcohol discovered in *Itea virginica L* and *Tylopilus plumbeoviolaceus*. It exhibits anti-obesity and hypoglycemic properties, reducing carcass and total body fat mass, and increasing cecal weight and short-chain fatty acid production. It is used in research related to obesity and diabetes.
- Orally active rare sugar alcohol
- Exhibits anti-obesity activities
- Exhibits hypoglycaemic activities
- Reduces carcass and total body fat mass
- Increases cecal weight, surface area, and short-chain fatty acid production
- Upregulates cecal microbial enzymes linked to butyrate metabolism
- Suitable for research on obesity and diabetes
Chem-Impex International, Inc. D(+)-Glucose, anhydrous | 50-99-7 | MFCD00148912 | 5KG
D(+)-Glucose, anhydrous, 50-99-7, MFCD00148912, 5KG
[C@@H](O)[C@@H](O)[C@H](O)C=O | 1g | 705364793](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000161756.jpg-250.jpg)
eMolecules 2438-80-4 | L-(-)-Fucose | Accela ChemBio (ASD) | MFCD00135607 | 164.157 | C6H12O5 | 98.000 | C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O | 1g | 705364793
L-(-)-Fucose | Accela ChemBio (ASD) | 2438-80-4 | MFCD00135607 | 164.157 | C6H12O5 | 98.000 | C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O | 1g | 705364793
[C@@H](O)[C@@H](O)[C@H](O)C=O | 25g | 602878556](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000159740.jpg-250.jpg)
eMolecules 2438-80-4 | L-(-)-Fucose | Oakwood Chemical | MFCD00135607 | 164.157 | C6H12O5 | 98.000 | C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O | 25g | 602878556
L-(-)-Fucose | Oakwood Chemical | 2438-80-4 | MFCD00135607 | 164.157 | C6H12O5 | 98.000 | C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O | 25g | 602878556
Chem-Impex International, Inc. D(+)-Mannose | 3458-28-4 | MFCD00064122 | 100G
D(+)-Mannose, 3458-28-4, MFCD00064122, 100G
Medchemexpress LLC Dibutyryl-cGMP sodium | 51116-00-8 | 99.7% | 100 MG
Dibutyryl-cGMP sodium is a cell-permeable cGMP analogue. It preferentially activates cGMP-dependent protein kinase (PKG), inhibits the release of [3H]-arachidonic acid from γ thrombin-stimulated human platelets, and induces peripheral antinociception through ATP-sensitive K+ channel activation.
- Cell-permeable cGMP analogue
- Preferentially activates cGMP-dependent protein kinase (PKG)
- Inhibits release of [3H]-arachidonic acid from γ thrombin-stimulated human platelets
- Induces peripheral antinociception via activation of ATP-sensitive K+ channels
- Induces process elongation and branching in astrocytes
- Prevents stress fibre formation and induces stellate morphology in cerebellar astrocytes
- Prevents RhoA-membrane association
- Accelerates wound closure in scratchwound model
- Antagonizes the hyperalgesic effect of PGE2