Sugar acids and derivatives
Medchemexpress LLC UDP-3-O-acyl-GlcNAc | 108636-29-9 | 1 MG
UDP-3-O-acyl-GlcNAc is an E. coli metabolite involved in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway. It has a molecular weight of 833.71 and a chemical formula of C31H53N3O19P2. This product is for research use only.
- Molecular weight: 833.71
- Formula: C31H53N3O19P2
- Initial source: Microorganisms (Escherichia)
- For research use only
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 1 ML
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase. Upon cleavage, it releases the fluorescent moiety 4-methylumbelliferyl (4-MU), which exhibits pH-dependent fluorescence excitation activity. Excitation wavelengths are 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), with emission wavelengths ranging from 445-455 nm as pH decreases.
- Used as a biomarker to quantify α-glucosidase activity in infant blood spot samples for Fabry and Pompe diseases.
- Intended for research use only.
- Not sold to patients.
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 10MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor provided as a high-purity research reagent for epigenetic and oncology studies. It is supplied as a powder in multiple pack sizes and displays cellular activity against AML MV4-11 cells, supporting biochemical and cell-based assays. Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- High purity (99.74%).
- Molecular formula C19H19N5O; molecular weight 333.39.
- Demonstrated inhibition of hIL-6 transcription and c-myc activity (IC50 ≤ 0.3 μM).
- Available in multiple pack sizes for flexible experimental design.
- Supplied as a powder with defined cold-storage stability.
Medchemexpress LLC Knt-127 | 1256921-89-7 | 99.6% | 10 MG
KNT-127 is a selective δ-opioid receptor agonist used in neuroscience research, reported to produce antidepressant-like and antinociceptive effects in preclinical models. CAS: 1256921-89-7. It is supplied as an off-white to light yellow solid with high purity and is suitable for in vitro and in vivo studies.
- Selective δ-opioid receptor agonist.
- Reported antidepressant-like and antinociceptive effects in animal models.
- High purity (99.6%).
- Molecular weight 372.46 g/mol.
- Soluble in DMSO at 25 mg/mL.
- Powder stable when stored at -20°C for extended periods.
- Suitable for in vitro pharmacology and in vivo behavioral studies.
- Available in small research quantities for laboratory use.
Medchemexpress LLC Miconazole (nitrate) | 22832-87-7 | >99.4% | 25 MG
Miconazole nitrate is an imidazole antifungal agent that can cross the blood-brain barrier and also possesses antibacterial effects. It functions by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes, making it effective against certain species of Leishmania protozoa.
- Imidazole antifungal agent
- Crosses the blood-brain barrier
- Possesses antibacterial effects
- Inhibits ergosterol synthesis
- Effective against Leishmania protozoa
- Used in Ektachrome film developing
Medchemexpress LLC Dodecanedioic acid-d4 | 97543-02-7 | 234.33 | 10 MG
Dodecanedioic acid-d4 is the deuterium labeled version of Dodecanedioic acid. Dodecanedioic acid is an orally active straight-chain dicarboxylic acid that acts as an alternative energy substrate. It can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion, and also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus.
- Deuterium labeled compound for quantitative tracing during drug development.
- Reduces muscle fatigue during exercise.
- Exhibits blood glucose-lowering activity.
Medchemexpress LLC MAC-545496 | 838810-96-1 | 98.0% | 10 MM * 1 ML
MAC-545496 is a potent nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR), demonstrating strong binding affinity (Kd ≤ 0.1 nM). It acts as an antivirulence agent, effectively reversing β-lactam resistance in Methicillin-resistant Staphylococcus aureus (MRSA) strains, and is intended for research use only.
- Potently synergizes with Cefuroxime and Oxacillin against S. aureus clinical isolates.
- Inhibits mprF expression in a concentration-dependent manner (IC50 of 0.0376 μg/mL).
- Inhibits citrate-induced biofilm formation in wild-type strains.
- Effective as monotherapy for MRSA-infected Galleria mellonella larvae, increasing survival.
Medchemexpress LLC Sapintoxin D | 80998-07-8 | 99.9% | 10 MG
Sapintoxin D is a fluorescent phorbol ester used to study the activation of protein kinase C (PKC). It functions as a calcium-dependent PKC activator, making it suitable for various research applications in cell biology and biochemistry.
- Fluorescent phorbol ester
- Activates protein kinase C (PKC)
- Calcium-dependent mechanism
- Appears as a white to off-white solid
- High purity of 99.91%
- Soluble in DMSO for in vitro studies
Medchemexpress LLC 2H-1-benzopyran-2-one, 7-(beta-D-glucopyranosyloxy)-4-methyl- | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 10MM 1ML
4-Methylumbelliferyl β-D-glucopyranoside is a coumarin-based fluorogenic substrate used to measure β-glucosidase and related enzyme activities. Enzymatic hydrolysis releases the fluorescent 4-methylumbelliferone (4-MU), which emits near 445-454 nm; excitation is pH-dependent. The product is supplied as a 10 mM solution in DMSO (1 mL) and is suitable for fluorescence-based biochemical assays.
Medchemexpress LLC Integrin alpha X bet 100ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Apexbio Technology LLC Beta-Lapachone 4707-32-8 10mg
Beta-Lapachone (CAS 4707-32-8) is a small molecule inhibitor of DNA topoisomerase I In DNA unwinding assays beta-Lapachone suppresses topoisomerase I-mediated DNA relaxation at concentrations as low as 1 M without inhibiting topoisomerase II or inducing topoisomerase I-dependent DNA cleavage It exhibits broad cytotoxicity against human cancer cell lines such as AD2780s HT-29 DLD G480 and MCF-7 with IC50 values ranging from 2 to 5 M The compound induces cell death through cytochrome c release triggering both apoptosis and necrosis and affects cell cycle progression causing S-phase and G2/M arrest in different carcinoma cell models Beta-Lapachone is widely utilized in studies investigating topoisomerase I inhibition cancer cell cytotoxicity and cell cycle regulation
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241055.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG
CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases with low-nanomolar inhibitory potency. It is used as a research reagent to investigate mitotic signaling and cell-cycle regulation and is supplied as a purified solid for in vitro studies.
- Potent dual Aurora A and B inhibitor with Ki ≈8-9 nM.
- Suitable for studying mitotic signaling and cell-cycle regulation in vitro.
- High purity (>99.0%) for reliable experimental results.
- Chemical formula C18H20N6OS; molecular weight 368.46 g·mol⁻¹.
- Available in multiple small-quantity pack sizes for laboratory use.
Selleck Chemical LLC D-Glucuronic acid
D-Glucuronic acid (D-Glucopyranuronic Acid) is a key intermediate metabolite of the uronic acid pathway and may plays a role in the detoxification of certain drugs
Medchemexpress LLC Guaiacylglycerol-bet 500mg
Guaiacylglycerol-beta-guaiacyl ether is a model compound of lignin monomers that can be degraded by Bacillus amyloliquefaciens CotA[1]
Medchemexpress LLC Hederacoside D | 760961-03-3 | MFCD22572710 | 99.3% | 1075.24 | C53H86O22 | 10 MG
Hederacoside D is a bioactive triterpenoid saponin isolated from Hedera helix (common ivy). It is provided as a white to off-white solid for research and analytical applications, with high purity and characterized molecular properties. Solubility data indicate excellent solubility in DMSO and formulations suitable for in vivo dosing studies.
- Bioactive triterpenoid saponin from Hedera helix.
- High purity (99.3%).
- Molecular formula C53H86O22 and molecular weight 1075.24.
- Soluble in DMSO at 100 mg/mL (may require ultrasonic).
- Supplied in small research pack sizes such as 10 mg.