Sugar acids and derivatives
Medchemexpress LLC Integrin alpha V bet 100ug | 100ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-His C-Avi labeled tag Integrin alpha V beta 3 Protein Human (HEK293 His-Avi) has molecular weight of 85-140 kDa
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC 5-bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt | 129541-41-9 | MFCD00135782 | 98.0% | 444.59 g/mol | C14H12BrClNNaO7 | 10 MG
X-Gluc sodium is the sodium salt of 5-bromo-4-chloro-3-indolyl β-D-glucuronide, a chromogenic substrate used to detect β-glucuronidase (GUS) activity. It reacts with GUS to produce an intense blue color and is commonly used in microbiology and molecular biology assays.
- Chromogenic substrate for β-glucuronidase detection
- Produces intense blue color upon enzymatic hydrolysis
- Suitable for bacterial contamination testing and GUS reporter assays
- High purity (98.0%) for reliable experimental results
- Sodium salt form improves handling and aqueous solubility
Medchemexpress LLC Saikosaponin D | 20874-52-6 | MFCD09028095 | >=90.0% | 780.98 g/mol | C42H68O13 | 10 MG
Saikosaponin D is a triterpene saponin isolated from Bupleurum used in research for its anti-inflammatory, antibacterial, antitumor, and anti-allergic activities. It has been reported to inhibit selectin-mediated binding and downstream signaling pathways including STAT3 and NF-κB, and to activate estrogen receptor-β.
- Triterpene saponin with multiple reported bioactivities including anti-inflammatory and antitumor effects.
- Suitable for in vitro and preclinical research at small mg scale.
- Molecular formula C42H68O13; molecular weight 780.98 g/mol.
- CAS number 20874-52-6 for unambiguous identification.
- Purity reported ≥90% by HPLC in vendor reference.