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Filtered Search Results
C(O)=O | 25g | 487539013](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000472521.jpg-250.jpg)
eMolecules 63039-48-5 | Boc-(S)-2-Propargylglycine | Acrotein ChemBio Inc. | MFCD01320855 | 213.233 | C10H15NO4 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 25g | 487539013
Boc-(S)-2-Propargylglycine | Acrotein ChemBio Inc. | 63039-48-5 | MFCD01320855 | 213.233 | C10H15NO4 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 25g | 487539013
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C(O)=O | 10g | 851114297](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 63039-48-5 | Boc-(S)-2-Propargylglycine | Acrotein ChemBio Inc. | MFCD01320855 | 213.233 | C10H15NO4 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 10g | 851114297
Boc-(S)-2-Propargylglycine | Acrotein ChemBio Inc. | 63039-48-5 | MFCD01320855 | 213.233 | C10H15NO4 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CC#C)C(O)=O | 10g | 851114297
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C(O)=O | 1g | 432789597](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492016.jpg-250.jpg)
eMolecules 23235-01-0 | L-PROPARGYLGLYCINE | AstaTech | MFCD00077855 | 113.116 | C5H7NO2 | 95.000 | N[C@@H](CC#C)C(O)=O | 1g | 432789597
L-PROPARGYLGLYCINE | AstaTech | 23235-01-0 | MFCD00077855 | 113.116 | C5H7NO2 | 95.000 | N[C@@H](CC#C)C(O)=O | 1g | 432789597
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Chem-Impex International, Inc. Boc-L-a-aminobutyric acid | 34306-42-8 | MFCD00037267 | 1G
Boc-L-a-aminobutyric acid, 34306-42-8, MFCD00037267, 1G
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Selleck Chemical LLC Itaconic acid S3095-1g
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Itaconic acid a macrophage-specific (M -specific) metabolite mediates crosstalk between macrophage metabolism and peritoneal tumors Itaconic acid is also a precursor of polymers chemicals and fuels that can be synthesized by many fungi
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C(O)=O | 10g | 257647373](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000160889.jpg-250.jpg)
eMolecules 23235-01-0 | L-Propargylglycine | Combi-Blocks | MFCD00077855 | 113.116 | C5H7NO2 | 98.000 | N[C@@H](CC#C)C(O)=O | 10g | 257647373
L-Propargylglycine | Combi-Blocks | 23235-01-0 | MFCD00077855 | 113.116 | C5H7NO2 | 98.000 | N[C@@H](CC#C)C(O)=O | 10g | 257647373
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Medchemexpress LLC Itaconic acid | 97-65-4 | MFCD00004260 | 100.0% | 130.10 g/mol | C5H6O4 | 100mg
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Itaconic acid (Standard) is the analytical standard of Itaconic acid This product is intended for research and analytical applications Itaconic acid a precursor of polymers chemicals and fuels can be synthesized by many fungi Itaconic acid also is a macrophage-specific metabolite Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors Itaconic acid has anti-inflammatory anti-microbial and immunomodulatory effect[1][2][4][5]
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Ambeed AMBEED
5000884632 ITACONIC ANHYDRIDE 500G
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AdipoGen Itaconic acid 4-octyl ester
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Chemical. CAS 3133-16-2. Formula C13H22O4. MW 242.3. Derivative of itaconate AG-CN2-0426 https//adipogen.com/ag-cn2-0426-itaconic-acid.html with enhanced cell permeability. Prodrug that is efficiently metabolized to itaconate in cells. Potent anti-inflammatory agent. In vitro it activates the transcription factor nuclear factor erythroid 2-related factor 2 Nrf2 also known as NFE2L2 in LPS-induced mouse and human macrophages. Upregulates Nrf2 levels via a newly identified post-translational modification, dicarboxylation of KEAP1. Alkylates cysteine residues 151, 257, 288, 273 and 297 on the protein KEAP1, enabling Nrf2 to increase the expression of downstream gene. Cysteine 151 is uniquely required for inhibiting KEAP1-mediated degradation of Nrf2 and mutating this residue in KEAP1 prevents the stabilization of Nrf2.
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AdipoGen Itaconic acid Itaconate
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Chemical. CAS 97-65-4. Formula C5H6O4. MW 130.1. Mammalian antibacterial metabolite. Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase PFKII inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. One of the most highly induced metabolites in activated macrophages. Exerts anti-inflammatory effects in vitro and in vivo. Regulates succinate levels by inhibiting succinate dehydrogenase SDH. Regulates mitochondrial respiration and cytokine production. Might induce inflammasome activation and consequently IL-1beta secretion by generating ROS.
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Medchemexpress LLC N-Propargylglycine | 58160-95-5 | 99.7% | C5H7NO2 | 25 MG
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N-Propargylglycine is a brain-penetrant, orally active PRODH inhibitor. It works by covalently modifying enzyme-bound FAD and active site lysine, leading to enzyme structural distortion, protein decay, and irreversible inhibition of proline and 4-hydroxyproline catabolism. It can induce UPRmt, upregulate mitochondrial chaperones, and enhance mitochondrial proteostasis.
- Brain-penetrant and orally active.
- Irreversibly inhibits proline oxidation.
- Induces mitochondrial unfolded protein response.
- Blocks astrocytic L-proline consumption.
- Stimulates neural processes and increases brain amino acid levels.
- Reduces hyperoxaluria and prevents calcium oxalate stone formation.
- Used in research for breast cancer, neurodegenerative disorders, and primary hyperoxaluria.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000402340 TERT-BUTYL 7-AMINOH 250MG
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NC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 436005529](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000473278.jpg-250.jpg)
eMolecules 198561-07-8 | Fmoc-L-Propargylglycine | AA Blocks LLC | MFCD01075095 | 335.359 | C20H17NO4 | 0.000 | OC(=O)[C@H](CC#C)NC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 436005529
Fmoc-L-Propargylglycine | AA Blocks LLC | 198561-07-8 | MFCD01075095 | 335.359 | C20H17NO4 | 0.000 | OC(=O)[C@H](CC#C)NC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 436005529
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Sigma Aldrich Fine Chemicals Biosciences Oleic acid natural fCC
Oleic acid is a monounsaturated fatty acid mainly found in high quantity in olive oil peanut oil sunflower oil and canola oil.
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Medchemexpress LLC Melinamide | 14417-88-0 | 99.9% | 383.61 g·mol-1 | C26H41NO | 25 MG
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Melinamide is an amide derivative of an unsaturated long-chain fatty acid used as a research tool to inhibit cholesterol absorption. It shows an IC50 of 20.9 μM for cholesterol uptake and inhibits acyl CoA:cholesterol acyltransferase (ACAT) activity in mucosal microsomes. For laboratory research use only.
- Purity 99.9%.
- CAS number 14417-88-0.
- Chemical formula C26H41NO.
- Molecular weight 383.61 g·mol-1.
- Activity IC50 20.9 μM for cholesterol absorption inhibition.
- Additional ACAT inhibition reported (50% inhibition at ~0.5 μM).
- Available as small-scale mg quantities and as a DMSO solution for research use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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