Fatty acid esters
Cayman Chemical 4-octyl Itaconate 250mg
A prodrug form of itaconate; hydrolyzed to itaconate by esterases in C2C12 cells and LPS-activated mouse macrophages; increases Nrf2 protein levels and expression of Nrf2 target genes and enhances LPS-induced Nrf2 stabilization in mouse macrophages; decreases serum levels of IL-1β and TNF-α, increases Nrf2 protein expression, and protects against LPS-induced lethality in wild-type, but not Nrf2 knockout, mice at 50 mg/kg
Selleck Chemical LLC Lithium acetoacetate S3353-1g
Lithium acetoacetate (LiAcAc Acetoacetic acid lithium salt Lithium 3-oxobutanoate) is an active endogenous metabolite that affects the growth of cells Lithium acetoacetate can be used as an acetoacetate standard for the measurement of acetoacetate in biological samples
Selleck Chemical LLC Sumatriptan Succinate S1432-25mg
Sumatriptan Succinate (GR 43175) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches
Selleck Chemical LLC Ribociclib succinate S5188-10mM/1mL
Ribociclib (LEE011) succinate is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively
Cayman Chemical 12-hydroxy LaurIc AcId 1g
A hydroxylated fatty acid; active against various bacteria (MICs = 6.25-125 μg/ml) and the fungus C. albicans (MIC = 15.63 μg/ml)
Medchemexpress LLC Monomethyl auristatin E intermediate-14 | 1932791-56-4 | C13H19NO2 | 50 MG
Monomethyl auristatin E intermediate-14 is a crucial reagent utilized in the synthesis of Monomethyl auristatin E. This intermediate supports the production of MMAE, a potent microtubule/tubulin inhibitor recognized for its significant anticancer activity. MMAE is frequently incorporated as the cytotoxic component in antibody-drug conjugates (ADCs).
- Intermediate for Monomethyl auristatin E synthesis
- Supports production of a microtubule/tubulin inhibitor
- Aids in the creation of anticancer agents
- Can be used as a component in antibody-drug conjugates
Apexbio Technology LLC Lauric Acid 143-07-7 500mg
Lauric acid (143-07-7) is a small-molecule modulator designed to induce apoptosis and inhibit microbial colonization thereby regulating cell viability and inflammatory responses Lauric acid exerts its biological activity primarily through ROS-dependent oxidative stress cell cycle arrest at S and G2/M phases and reduction of intracellular glutathione In cell-based studies lauric acid induces apoptosis in colon carcinoma cells (Caco-2 and IEC-6) and reduces Propionibacterium acnes colonization in animal models Based on these pharmacological properties lauric acid holds research potential in investigating antiproliferative mechanisms in cancer and antimicrobial applications including acne treatment
Chem-Impex International, Inc. 4-Bromobutyric acid methyl ester | MFCD00041482 | 100G
4-Bromobutyric acid methyl ester, MFCD00041482, 100G
Medchemexpress LLC Chlorothalonil (Standard) | 1897-45-6 | MFCD00045594 | 25 MG
Chlorothalonil (Standard) is an analytical standard and broad-spectrum foliar fungicide. It is intended for research and analytical applications, effectively combating fungal diseases in various vegetable and crop leaves. Studies indicate its potential to alter the soil's microbial community, inhibit spermatogenesis, and contribute to intestinal epithelial barrier dysfunction and fetal toxicity.
- Analytical standard for research and analytical applications
- Broad-spectrum foliar fungicide
- Combats fungal diseases in vegetables and crops
- May alter soil microbial community
Medchemexpress LLC Ethyl palmitate | 628-97-7 | 1000 G
Ethyl palmitate is a CHIKV virus inhibitor with an EC50 value of 0.0068 μM. It demonstrates anti-inflammatory activity by reducing levels of TNF-α, IL-6, and NF-κB in endotoxemic rats.
- Inhibits the expression and viral activity of CHIKV virus E2 protein
- Decreases plasma levels of TNF-α and IL-6
- Reduces NF-κB expression in liver and lung tissues
- Ameliorates histopathological changes caused by LPS in a rat model
- Inhibits phagocytic function of the reticuloendothelial system (RES)
Cayman Chemical Lauric Acid Fatty Acids and De
A medium-chain fatty acid; has been found at high levels in coconut oil; induces the activation of NF-κB and the expression of COX-2, iNOS, and IL-1α in RAW 264.7 cells at 25 µM