Glycerolipids
Medchemexpress LLC Tristearin | 555-43-1 | ≥98.0% | 1 G
Tristearin, also known as Glycerol tristearate, is a triglyceride composed of three units of stearic acid. It is intended for research use only. This compound is frequently utilized as a component in solid-lipid nanoparticles (SLNs) for the development of advanced drug delivery systems, increasing the cellular uptake rate of carried drugs and thereby enhancing drug efficacy.
- Increases cellular uptake rate of carried drugs
- Enhances drug efficacy
- Molecular weight: 891.48
- Chemical formula: C57H110O6
- Appearance: White to off-white solid
- Initial source: Plants
- Shipping: Room temperature (continental US)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Tristearin (Glycerol tristearate) | 555-43-1 | ≥98.0% | 100 MG
Tristearin (Glycerol tristearate) is a triglyceride derived from three units of stearic acid. It is also a commonly used solid-lipid nanoparticle (SLN) component for constructing drug delivery carriers, which increases the cellular uptake rate of carried drugs, thereby enhancing drug efficacy.
- Derived from three units of stearic acid
- Used as a solid-lipid nanoparticle (SLN) component
- Increases cellular uptake rate of carried drugs
- Enhances drug efficacy
Sigma Aldrich Fine Chemicals Biosciences Castor Oil | 8001-79-4 | MFCD00130746 | 250ml
Castor Oil | 8001-79-4 | MFCD00130746 | 250ml
Medchemexpress LLC Triolein-13C3 | 82005-46-7 | 888.41 | 5 MG
Triolein-13C3 is the 13C-labeled Triolein. Triolein is a symmetrical triacylglycerol with strong antioxidant and anti-inflammatory properties.
- Reduces MMP-1 upregulation
- Suitable as a tracer for quantitation
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Sigma Aldrich Fine Chemicals Biosciences 12-Distearoyl-sn-gycero-3100MG
Non-pyrogenic well-defined liposomes loaded with a molecule of choice are formed by a single hydration step.
Sigma Aldrich Fine Chemicals Biosciences Castor oil meets testing specifications per USP | 8001-79-4 | MFCD00130746 | 500ML
Castor oil meets testing specifications per USP | 8001-79-4 | MFCD00130746 | 500ML
Sigma Aldrich Fine Chemicals Biosciences 12 Distearoyl sn glycero 31G
Non-pyrogenic well-defined liposomes loaded with a molecule of choice are formed by a single hydration step.
Medchemexpress LLC Triolein | 122-32-7 | 885.43 | 1 ML
Triolein is a symmetric triacylglycerol known for its ability to reduce the upregulation of MMP-1, an enzyme involved in various physiological and pathological processes. It also exhibits potent antioxidant and anti-inflammatory properties.
- Reduces upregulation of MMP-1 in dermal fibroblasts.
- Possesses strong antioxidant activities.
- Demonstrates strong anti-inflammatory activities.
- Decreases the upregulation of MMP-1 in dermal fibroblasts produced by reactive oxygen species.
- Can improve oxidative stress induced by oxidative low-density lipoprotein in endothelial cells.
Sigma Aldrich Fine Chemicals Biosciences Glyceryl tridecanoate 99 G1G
REAGENT Glyceryl tridecanoate 99 G1G
Medchemexpress LLC Tricaproin 1mL
TricaproinIt is an organic compound belonging to the class of triacylglycerols It consists of three molecules of caproic acid esterified to the glycerin backbone with a mild fatty smell TricaproinIt has a variety of applications in the cosmetic and personal care industries especially as an emollient and conditioning agent in skin and hair care products Additionally it is used as a lubricant and surfactant in industrial settings
Medchemexpress LLC Tributyrin (glyceryl tributyrate) | 60-01-5 | 98.9% | 302.36 | 1 ML
Tributyrin (Glyceryl tributyrate) is a neutral short-chain fatty acid triglyceride that acts as a stable and rapidly absorbed proagent of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. It has potent antiproliferative, proapoptotic, and differentiation-inducing effects.
- Induces significant growth inhibition in PC-3 cells
- Causes G1 cell cycle arrest in LNCaP cells
- Induces higher apoptosis rates in PC-3 and TSU-PR1 cells
- Induces prostate-specific antigen expression in LNCaP cells
- Directly inhibits the production of TNF-α and IL-1β in RAW 264.7 cells under LPS stimulation
- Improves metabolic and inflammatory states in high-fat diet-induced obese mice
- Significantly improves gut microbiota dysbiosis and intestinal injury in a gut dysfunction mouse model
Medchemexpress LLC Triacetin | 102-76-1 | 99.6% | 1 ML
Triacetin (Glyceryl triacetate) is a synthetic, orally active compound that increases acetate bioavailability in glioma cells. It induces glioma cell growth arrest and apoptosis, freely crossing the blood brain barrier/plasma membrane. This compound also increases histone acetylation and enhances the chemotherapeutic efficacy of Temozolomide. It is intended for research use only.
- Induces growth arrest in various glioma cells
- Inhibits U87MG cell viability
- Induces apoptosis in GBM cancer cells
- Decreases class I and II HDAC mRNA expression
- Inhibits HDAC-8 activity
- Activates mTOR complexes downstream genes
- Increases tumor suppressor miRs
- Enhances chemotherapeutic efficacy with Temozolomide
- Increases survival in animal models with GBM-derived GSCs