Steroids and derivatives
Selleck Chemical LLC U18666A-5mg
U18666A (U18) is an inhibitor of intra-cellular cholesterol transport that inhibits dengue virus entry and replication.
Medchemexpress LLC β-estradiol-6-CMO-PEG3-biotin | 2938875-38-6 | 97.8% | 759.95 g·mol⁻¹ | C38H57N5O9S | 1 MG
β-Estradiol-6-CMO-PEG3-biotin is a biotinylated estradiol derivative used as a cleavable three-unit polyethylene glycol (PEG3) linker for antibody-drug conjugate (ADC) synthesis. It provides a hydrophilic spacer and a biotin handle to facilitate conjugation, affinity capture, and detection in downstream assays.
- Cleavable three-unit PEG linker providing hydrophilicity and spacing.
- Biotin tag enables affinity capture and detection.
- High purity (97.82%) suitable for research applications.
- Soluble in DMSO at ≥ 50 mg/mL; use freshly opened DMSO.
- Stable as a powder at -20°C for up to 3 years; limited stability in solvent as specified by manufacturer.
Selleck Chemical LLC Vitamin A Acetate S4083-50mg
Vitamin A Acetate (Retinyl Retinol) is a group of unsaturated nutritional hydrocarbons that includes retinol retinal retinoic acid and several provitamin A carotenoids among which beta-carotene is the most important
Medchemexpress LLC Cagrilintide acetate | 1415456-99-3 | CB712152538 | 99.96% | 4409.01 | 5 MG
Cagrilintide acetate is a non-selective AMYR/CTR agonist and a long-acting acylated amylase analogue. It reduces food intake and causes significant weight loss in a dose-dependent manner, making it suitable for obesity studies.
- Non-selective AMYR/CTR agonist
- Long-acting acylated amylase analogue
- Reduces food intake
- Causes significant weight loss in a dose-dependent manner
- Suitable for obesity studies
- For research use only
Medchemexpress LLC Cortisone acetate (Standard) | 50-04-4 | 99.9% | 402.48 | 25 MG
Cortisone acetate is an oxidized metabolite of Cortisol (a Glucocorticoid). It acts as an immunosuppressant and anti-inflammatory agent and can partially intervene in the binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations. This product is intended for research and analytical applications.
- Attenuates apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) dose-dependently.
- Decreases BCG lesions and tuberculin reactions in rabbits.
Medchemexpress LLC Dexamethasone palmitate | 14899-36-6 | 99.7% | 50 MG
Dexamethasone palmitate (DXP) is a prodrug of Dexamethasone, primarily utilized in inflammation research. It has demonstrated in vitro anti-inflammatory effects by decreasing LPS-induced MCP-1 and TNF-α concentrations in RAW 264.7 cells. In vivo studies in New Zealand White rabbits have shown that Dexamethasone palmitate, administered via IVT injection, distributes significantly in the vitreous humor and can control VEGF-induced vascular hyperpermeability.
- Appearance: Solid, white to off-white
- Purity: 99.68%
- Molecular weight: 630.87
- Formula: C38H59FO6
- Primarily for inflammation research
- Demonstrates in vitro anti-inflammatory effects (decreases LPS-induced MCP-1 and TNF-α)
- In vivo studies show significant distribution in vitreous humor and control of VEGF-induced vascular hyperpermeability
Medchemexpress LLC Cortisone (Standard) | 53-06-5 | 98.5% | 360.44 | 100 MG
Cortisone (Standard) is the analytical standard of Cortisone, intended for research and analytical applications. It is an oxidized metabolite of Cortisol (a Glucocorticoid), and acts as an immunosuppressant and anti-inflammatory agent. This product is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS, and can partially intervene in the binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations.
- Analytical standard for Cortisone.
- Intended for research and analytical applications.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Acts as an immunosuppressant and anti-inflammatory agent.
Cayman Chemical Estrone Steroid Hormones
A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
Abcam 20-Hydro x yecdysone (Ecdysterone), Steroid invertebrate hormone, 25MG
MW 480.6 Da, Purity >98%. Steroid invertebrate hormone. Regulates molting, metamorphosis and reproduction in arthropods. Neuroprotective against oxidative stress in mammals. Inhibits NF-κB activation and iNOS expression. Antioxidant and apoptotic agent.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical LnolIn VItamIn D3 1g
A biologically inactive precursor to calcitriol converted to active metabolites in vivo; obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3; can be converted to 25-hydroxy vitamin D3 in the liver by CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney
Sigma Aldrich Fine Chemicals Biosciences Hydrocortisone Impurity D100MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Sigma Aldrich Fine Chemicals Biosciences alpha Estradiol powder 98500MG
alpha Estradiol powder 98500MG