Steroids and derivatives
Medchemexpress LLC Estradiol 3-sulfamate | 172377-52-5 | 351.46 | 5 MG
Estradiol 3-sulfamate is a potent, long-acting, and orally active steroid sulfatase inhibitor. It inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM.
- Potent, long-acting, and orally active steroid sulfatase inhibitor.
- Inhibits estrone sulfatase.
- Used for research purposes.
Sigma Aldrich Fine Chemicals Biosciences alpha Estradiol powder 98500MG
alpha Estradiol powder 98500MG
Medchemexpress LLC Estradiol 17-(β-D-Glucuronide) sodium | 15087-02-2 | 98.9% | 50 MG
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. It functions as a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). This compound regulates and inhibits MRP8-mediated transport processes and can be used in studies related to intrahepatic cholestasis, as it induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats.
- Metabolite of natural estrogen
- Substrate of Oatp and Mrp2
- Regulates and inhibits MRP8-mediated transport processes
- Induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis
- Useful in studies related to intrahepatic cholestasis
- Solid, white to off-white appearance
- Molecular weight of 470.49
- Chemical formula C24H31NaO8
Medchemexpress LLC Estradiol 3-sulfamate | 172377-52-5 | 351.46 | 1 ML
Estradiol 3-sulfamate is a potent, long-acting, and orally active steroid sulfatase inhibitor. It effectively inhibits estrone sulfatase with specific IC50 and Ki values, making it suitable for various research applications.
- Potent steroid sulfatase inhibitor
- Long-acting steroid sulfatase inhibitor
- Orally active
- Inhibits estrone sulfatase with an IC50 of 251 nM
- Inhibits estrone sulfatase with a Ki of 133 nM
- For research use only
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Cayman Chemical 17-EstradIol-d3 1mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS
Cayman Chemical 17-EstradIol-d3 5mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS
Cayman Chemical EstradIol CypIonate 1g
A synthetic estrogen; reduces estrogen-depletion induced spikes in basal tail temperature in ovariectomized wild-type, ERα-/-, and ERβ-/- mice at 0.1 mg/kg per day; increases the rate of pregnancy in cows induced to ovulate small dominant follicles; reduces edema and articular joint neutrophil infiltration in an ovariectomized mouse model of zymosan-induced arthritis
Medchemexpress LLC Estradiol (Standard) | 50-28-2 | 99.9% | 1 ML
Estradiol (β-Estradiol) is a steroid hormone and the primary female sex hormone. It can increase the expression of neural markers in human endometrial stem cells (hEnSCs) and promote their neural differentiation. This product is intended for research use only and is utilized in studies concerning cancers, neurodegenerative diseases, and neural tissue engineering.
- Increases expression of neural markers in human endometrial stem cells.
- Promotes neural differentiation of human endometrial stem cells.
- Utilized in research for cancers, neurodegenerative diseases, and neural tissue engineering.
- Increases SIRT1 protein levels in C2C12 cells.
- Increases FoxL2 and pFoxL2 protein expression levels in ZF4 cells.
- Promotes proliferation of sheep myoblasts.
- Enhances expression of ERRα and VLDL-related genes in primary hepatocytes.
- Induces mRNA expression of pS2 and NRF1 genes in MCF-7 cells.
Gold Biotechnology Inc Digitonin Special Grade
Digitonin is a nonionic saponin steroid derived from the plant Digitalis purpurea It is useful for creating Digitonin-cholesterol complexes which form when Digitonin disrupts the cell membrane and binds with cholesterol in a nearly 1 1 stoichiometric ratio When precipitated from ethanolic solutions these complexes form flat lamellar sheets Digitonin s cholesterol displacing properties have been used in newer applications to quantify the rate of lysosomal membrane permeabilization (LMP) a new technique developed to bypass traditional cell death pathways Digitonin permeabilizes plasma membranes but leaves lysosomal membranes intact allowing for a quantifiable measurement of lysosomal hydrolases and comparison to normal cellular enzyme activity Digitonin has been shown to induce hemolysis in red blood cells
Sigma Aldrich Fine Chemicals Biosciences 5beta Cholestan 3alpha ol500MG
5beta Cholestan 3alpha ol500MG
Perkin Elmer US LLC Gateway Controller for ATR Trough Top Plate - ZnSe, UK
The controller has a temperature range from ambient to 200°C, in 1°C increments. This controller is compatible with the Spectrum 3/Frontier spectrometer.