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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose); can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
CA15-3 (Carcinoma antigen 15-3) is also known as MUC 1 antigen It is a membrane-anchored mucin-type glycoprotein present in malignant cells It is used as tumor marker to monitor breast cancer treatment and disease recurrence
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6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
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6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
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2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
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2-Deoxyadenosine (CAS 958-09-8) is a synthetic purine nucleoside analog that functions as a demethylated nucleoside in biological systems Structurally similar to adenosine but lacking a hydroxyl group at the 2 position it selectively pairs with deoxythymidine during DNA synthesis 2-Deoxyadenosine influences regulatory pathways associated with DNA replication and repair serving as a molecular probe to study these processes It is extensively utilized in molecular biology and genomics for investigating DNA synthesis repair mechanisms and the dynamics of nucleic acid metabolism
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Also available in 1 mL, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. Purity 97.13%
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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A deoxyribonucleoside, may be used by some cells as an energy source under energy stress conditions and to affect cAMP levels. It is used in comparison studies of the functions of adenosine analogues on various biological processes. Specifications:Ultra Pure GradeEM (259nm, phosphate buffer, pH 7.0): >14,500Appearance: White crystalline powderChEBI : Not available.Crystal_Structure : Not available.InChI : Not available.InChIKey : Not available.Melting Point: 187-189 °CRTECS Number: AU7358600
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2 -Deoxyadenosine 5 -monophosphate disodium a nucleic acid AMP derivative is a deoxyribonucleotide found in DNA 2 -Deoxyadenosine 5 -monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]
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