Pyrimidine nucleosides
Gemcitabine Hydrochloride 98.0+%, TCI America™
CAS: 122111-03-9 Molecular Formula: C9H12ClF2N3O4 Molecular Weight (g/mol): 299.659 MDL Number: MFCD01735988 InChI Key: OKKDEIYWILRZIA-OSZBKLCCSA-N Synonym: gemcitabine hcl,2',2'-difluorodeoxycytidine monohydrochloride,2'-deoxy-2',2'-difluorocytidine hydrochloride,2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl PubChem CID: 44558863 ChEBI: CHEBI:31647 IUPAC Name: 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride SMILES: [H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-]
(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine 98.0+%, TCI America™
CAS: 863329-66-2 Molecular Formula: C10H13FN2O5 Molecular Weight (g/mol): 260.22 MDL Number: MFCD19982668 InChI Key: ARKKGZQTGXJVKW-UHFFFAOYNA-N Synonym: PSI-6206 PubChem CID: 11311503 IUPAC Name: 1-[3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione SMILES: CC1(F)C(O)C(CO)OC1N1C=CC(=O)NC1=O
5-Ethynyl-2'-deoxyuridine 98.0+%, TCI America™
CAS: 61135-33-9 Molecular Formula: C11H12N2O5 Molecular Weight (g/mol): 252.23 MDL Number: MFCD01675687 InChI Key: CDEURGJCGCHYFH-DJLDLDEBSA-N Synonym: EdU PubChem CID: 472172 IUPAC Name: 5-ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(C#C)C(=O)NC1=O
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil 98.0+%, TCI America™
CAS: 69123-98-4 Molecular Formula: C9H10FIN2O5 Molecular Weight (g/mol): 372.091 MDL Number: MFCD00866922 InChI Key: IPVFGAYTKQKGBM-BYPJNBLXSA-N Synonym: Fialuridine, FIAU, 2′C-Fluoro-5-iodoarauracil PubChem CID: 50313 IUPAC Name: 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)F)I
5-Ethynyl-2'-deoxycytidine 98.0+%, TCI America™
CAS: 69075-47-4 Molecular Formula: C11H13N3O4 Molecular Weight (g/mol): 251.242 MDL Number: MFCD22417249 InChI Key: HMJSYXIPNSASJY-IWSPIJDZSA-N Synonym: EdC PubChem CID: 90176383 IUPAC Name: 4-amino-5-ethynyl-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one SMILES: C#CC1=CN(C(=O)N=C1N)C2CC(C(O2)CO)O
2'-Deoxy-5-fluorocytidine 98.0+%, TCI America™
CAS: 10356-76-0 Molecular Formula: C9H12FN3O4 Molecular Weight (g/mol): 245.21 MDL Number: MFCD00077348 InChI Key: IDYKCXHJJGMAEV-UHFFFAOYNA-N PubChem CID: 515328 IUPAC Name: 4-amino-5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one SMILES: NC1=NC(=O)N(C=C1F)C1CC(O)C(CO)O1
2'-Deoxycytidine 98.0+%, TCI America™
CAS: 951-77-9 Molecular Formula: C9H13N3O4 Molecular Weight (g/mol): 227.22 MDL Number: MFCD00006547 InChI Key: CKTSBUTUHBMZGZ-JORGKRSHNA-N Synonym: 2'-deoxycytidine,deoxycytidine,dcyd,cytosine deoxyriboside,cytidine, 2'-deoxy,deoxyribose cytidine,desoxycytidin german,4-amino-1-2r,4s,5r-4-hydroxy-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one,cytosine, deoxyribonucleoside,d-cytidine PubChem CID: 13711 ChEBI: CHEBI:15698 IUPAC Name: 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one SMILES: NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1
3'-Azido-3'-deoxythymidine 98.0+%, TCI America™
CAS: 30516-87-1 Molecular Formula: C10H13N5O4 Molecular Weight (g/mol): 267.25 MDL Number: MFCD00006536 InChI Key: HBOMLICNUCNMMY-CFQLRCIDNA-N Synonym: azt; azidothymidine; zdv; zidovudine,1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione PubChem CID: 455007 IUPAC Name: 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione SMILES: CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
2'-Azido-2'-deoxyuridine 98.0+%, TCI America™
CAS: 26929-65-7 Molecular Formula: C9H11N5O5 Molecular Weight (g/mol): 269.217 MDL Number: MFCD00043045 InChI Key: MRUKYOQQKHNMFI-XVFCMESISA-N Synonym: 2'-azido-2'-deoxyuridine,n3-du,uridine,2'-azido-2'-deoxy,2 inverted exclamation marka-azido-2 inverted exclamation marka-deoxyuridine,1-2r,3r,4s,5r-3-azido-4-hydroxy-5-hydroxymethyl oxolan-2-yl-3h-pyrimidine-2,4-dione,2'-azido,2'-deoxyuridine,2'-azido-2'-desoxyuridine,2'-deoxy-2'-azido-uridine,2'-azido-2'-deoxy uridine,uridine, 2'-azido-2'-deoxy PubChem CID: 168629 IUPAC Name: 1-[(2R,3R,4S,5R)-3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)N=[N+]=[N-]
Thiophosphoryl Chloride 98.0+%, TCI America™
CAS: 3982-91-0 Molecular Formula: Cl3PS Molecular Weight (g/mol): 169.384 MDL Number: MFCD00011504 InChI Key: WQYSXVGEZYESBR-UHFFFAOYSA-N Synonym: Phosphorus Thiochloride PubChem CID: 19883 IUPAC Name: trichloro(sulfanylidene)-$l^{5}-phosphane SMILES: P(=S)(Cl)(Cl)Cl
Cayman Chemical 5-Formyl-2-deoxyurIdIn 10mg
A RIPK1 inhibitor selectively binds to RIPK1 over RIPK3 (Kds 85 and 10000 nM respectively) inhibits necrosome formation and phosphorylation of RIPK1 induced by TNF-a SM-164 and Z-VAD-FMK in HT-29 cells (EC50 22.4 nM) decreases reductions in body temperature and improves survival in a mouse model of TNF-a- and Z-VAD-FMK-induced SIRS at 10 and 20 mg/kg reduces lung RIPK1 phosphorylation IL-6 and TNF-a levels and total protein content as well as decreases the number of hemorrhagic sites and congestion edema in a mouse model of short-term intratracheal NNK exposure-induced ALI
Cayman Chemical 2-Fluoro-2-deoxyurIdIn 25mg
A P2Y6 receptor agonist selectively induces inositol phosphate accumulation in 1321N1 cells expressing P2Y6 receptors (EC50 28 nM) over those expressing P2Y1 P2Y2 or P2Y4receptors at 10 UM induces DNA synthesis in isolated rat aorta smooth muscle cells at 1 UM
Cayman Chemical 2-DeoxyurIdIn 500mg
A peptide substrate for MMP-1 improved kcat/Km ratio compared with Dnp-PLGLWA-DArg-NH2
Cayman Chemical DeoxyurIdIn 5-monphosphate 1g
Immunogen Recombinant SARS-CoV nucleocapsid protein Host Mouse Species Reactivity ( ) SARS-CoV SARS-CoV-2 (-) MERS-CoV HCoV-229E HCoV-NL63 HCoV-HKU1 HCoV-OC43 Applications ELISA WB (reducing conditions)
Cayman Chemical 5-Formyl-2-deoxyurIdIn 100mg
13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian LOs. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 UM{592880} and down regulates the expression of the IRGpIIb/IIIa receptor.{591}