Drug Standards
Apexbio Technology LLC Econazole 27220-47-9 5g
Econazole (CAS 27220-47-9) is an imidazole-derived antifungal agent targeting cytochrome P450-dependent enzymes It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal membrane integrity and cell growth Econazole exerts its biological activity primarily through inhibition of cytochrome P450-dependent enzymes In experimental models involving fungi-mediated dermal infections and other dermatological assays econazole demonstrates inhibitory activity with reported IC50 values generally in the micromolar range depending on the fungal strain and specific assay employed Based on these pharmacological properties econazole holds research potential in dermatological and microbiological applications including investigations of fungal pathogenic mechanisms cellular susceptibility and resistance pathways
Apexbio Technology LLC Doxazosin 74191-85-8 100mg
Doxazosin (CAS 74191-85-8) is a synthetic quinazoline derivative that functions as a selective antagonist of postsynaptic 1-adrenergic receptors By inhibiting these receptors doxazosin reduces vascular smooth muscle contraction leading to decreased peripheral resistance This pharmacological profile is valuable for research investigating 1-adrenergic signaling pathways vascular tone regulation and cardiovascular physiology Doxazosin is commonly utilized in studies related to hypertension benign prostatic hyperplasia and receptor pharmacology
Apexbio Technology LLC Camostat Mesilate 59721-29-8 100mg
Camostat Mesilate (59721-29-8) is a small-molecule inhibitor targeting trypsin-like serine proteases It is designed to suppress protease activity thereby modulating processes such as epithelial sodium channel (ENaC) function and airway surface liquid homeostasis Camostat Mesilate exerts its biological activity primarily through protease inhibition In cell-based studies using airway epithelial cells Camostat Mesilate demonstrates ENaC activity suppression with an IC50 value of 50 nM Based on these pharmacological properties Camostat Mesilate holds research potential in studies of respiratory physiology and pathophysiology particularly those investigating ENaC-mediated ion transport in airway epithelial cell models
Selleck Chemical LLC Larotrectinib
Larotrectinib (Vitrakvi LOXO-101 ARRY-470) is an ATP-competitive oral administered and highly selective inhibitor of the tropomyosin-related kinase (TRK) family receptors
Apexbio Technology LLC Spironolactone 52-01-7 5g
Spironolactone (52-01-7) is a small-molecule antagonist targeting mineralocorticoid (aldosterone) and androgen receptors It is designed to block receptor-mediated signaling thereby affecting sodium and potassium balance and pathways related to androgen signaling Spironolactone exerts its biological activity primarily through competitive inhibition of mineralocorticoid and androgen receptors In in vitro studies spironolactone demonstrates antagonistic activity with an IC50 value of 24 nM for mineralocorticoid receptors and 77 nM for androgen receptors Based on these pharmacological properties spironolactone holds research potential in studies of hormone signaling sodium homeostasis and androgen receptor-mediated gene expression in endocrine or cancer research
Apexbio Technology LLC Neostigmine Bromide 114-80-7 100mg
Neostigmine Bromide (CAS 114-80-7) is a synthetic quaternary ammonium compound that acts as a reversible inhibitor of acetylcholinesterase (AChE) By blocking AChE activity neostigmine bromide prolongs the action of acetylcholine at neuromuscular junctions and cholinergic synapses thereby enhancing muscarinic and nicotinic receptor-mediated effects This compound is frequently studied in contexts involving neuromuscular function and its use extends to research on disorders such as myasthenia gravis postoperative urinary retention paralytic ileus and primary open-angle glaucoma Additionally it is investigated as an adjuvant for local anesthetics and opioids in pain management following gynecological or abdominal surgery
Medchemexpress LLC Tofacitinib Impurity T | 1675248-19-7 | 99.8% | C16H22N6O2 | 50 MG
Tofacitinib Impurity T is a drug intermediate, also known as 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide. This compound is suitable for the synthesis of various active compounds.
- Purity of 99.8%
- Solid appearance
- Ships at room temperature within continental US
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- For research use only
Apexbio Technology LLC Abacavir sulfate 188062-50-2 10mg
Abacavir sulfate (188062-50-2) is a small-molecule inhibitor targeting HIV reverse transcriptase It is designed to inhibit reverse transcriptase activity thereby blocking viral DNA synthesis Abacavir sulfate exerts its biological activity primarily through intracellular conversion to its active triphosphate form which competes with endogenous substrates to terminate viral nucleic acid polymerization In cell-based studies Abacavir sulfate demonstrates inhibitory activity with an IC50 range of 1 2 to 6 2 M depending on the cell line and experimental protocol Based on these pharmacological properties Abacavir sulfate holds research potential in antiviral research particularly for in vitro HIV infection assays and resistance pathway analyses
Apexbio Technology LLC Ranitidine 66357-59-3 500mg
Ranitidine (CAS 66357-59-3) is a small-molecule antagonist targeting histamine H2 receptors It is designed to competitively inhibit histamine binding to H2 receptors on gastric parietal cells thereby reducing gastric acid secretion Ranitidine exerts its biological activity primarily through blockade of histamine H2 receptors In experimental pharmacological assays ranitidine demonstrates antagonist activity with an IC50 value of approximately 3 3 1 4 M Based on these pharmacological properties ranitidine holds research potential in studies of gastric acid-related physiology gastrointestinal ulcer models and pharmacological interventions involving histaminergic pathways
Apexbio Technology LLC Robenidine hydrochloride 25875-50-7 200mg
Robenidine hydrochloride (CAS 25875-50-7) is a small-molecule antimicrobial agent with activity against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) It is designed to inhibit these bacterial pathogens thereby interfering with microbial survival Robenidine hydrochloride exerts its biological activity primarily through disruption of microbial cell membrane integrity In in vitro studies Robenidine hydrochloride demonstrates inhibitory activity with MIC50 values of 8 1 M for MRSA and 4 7 M for VRE Based on these pharmacological properties Robenidine hydrochloride holds research potential in the fields of microbial infection drug resistance and the development of novel anti-infective strategies
Apexbio Technology LLC Norfloxacin 70458-96-7 10g
Norfloxacin (70458-96-7) is a small-molecule inhibitor targeting bacterial DNA gyrase It is designed to inhibit DNA gyrase thereby interfering with bacterial DNA replication and transcription Norfloxacin exerts its biological activity primarily through inhibition of topoisomerase activity by binding to bacterial DNA gyrase disrupting DNA supercoiling and strand separation Norfloxacin demonstrates broad-spectrum antibacterial inhibition with reported IC50 values ranging from approximately 0 1 to 10 M depending on bacterial species and assay conditions Based on these pharmacological properties norfloxacin holds research potential in studies of bacterial DNA replication mechanisms antimicrobial susceptibility assays and resistance analyses
Medchemexpress LLC Nintedanib impurity 5 | 676326-36-6 | C₁₂H₁₁NO₄ | 50 MG
Nintedanib impurity 5 is an impurity of Nintedanib.
- CAS Number: 676326-36-6
- Molecular Formula: C₁₂H₁₁NO₄
- Molecular Weight: 233.22
- Storage: Store at room temperature for 3 years; in solvent -80°C for 2 years; -20°C for 1 year.
Selleck Chemical LLC Berzosertib
Berzosertib (VE-822 VX970 M6620) is an ATR inhibitor with IC50 of 19 nM in HT29 cells
Sigma Aldrich Fine Chemicals Biosciences Trospium chloride Related Compound B United States Pharmacopeia (USP) Reference Standard | 63516-30-3 | 20MG
Trospium chloride Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 373.87 | 63516-30-3 | 20MG
Sigma Aldrich Fine Chemicals Biosciences Flurbiprofen impurity A European Pharmacopoeia (EP) Reference Standard | 6341-72-6 |
Flurbiprofen impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 226.27 | 6341-72-6 |