Drug Standards
Medchemexpress LLC CPD-1224 | 2891620-68-9 | C43H47ClN8O7S | 100 MG
CPD-1224 is an orally effective ALK inhibitor derived from an ALK inhibitor that connects to the cereblon ligand. It targets the EML4-ALK oncogenic fusion protein, leading to the degradation of both ALK and its mutant forms L1196M/G1202R. This compound has the potential to slow down tumor growth and is for research use only.
- Enhances kinase binding selectivity and exhibits good degradation selectivity
- Shows antiproliferative activity against mouse Ba/F3 cells
- Demonstrates oral bioavailability of 28% in mice (10 mg/kg, oral)
- Inhibits tumor growth in mice by reducing total ALK and phosphorylated ALK levels
Medchemexpress LLC Ticagrelor impurity 10 | 2803420-77-9 | 98.5% | C26H32F2N6O4S | 5 MG
Ticagrelor impurity 10 is an impurity of Ticagrelor, intended for research use only. This chemical reagent has a molecular weight of 562.63 and appears as a white to off-white solid.
- Impurity of ticagrelor
- For research use only
- Molecular weight of 562.63
- Appears as a white to off-white solid
- Shipped at room temperature in continental US
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Selleck Chemical LLC Fenoldopam mesylate S4618-200mg
Fenoldopam (SKF 82526 Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties It lowers blood pressure through arteriolar vasodilation
Medchemexpress LLC (rel)-Tivantinib | 905853-99-8 | 96.5% | C23H19N3O2 | 100 MG
(rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. It also targets GSK3α and GSK3β, which are important in the cellular mechanism of non-small cell lung cancer (NSCLC).
- Potent and highly selective inhibitor of c-MET
- Targets GSK3α and GSK3β
Medchemexpress LLC Diclazuril | 101831-37-2 | 99.7% | 100 MG
Diclazuril (R-64433) is a potent and orally active anticoccidial agent, a benzeneacetonitrile derivative. It is used in the research of certain infectious and parasitic diseases.
- Potent and orally active anticoccidial agent
- Used in research for infectious and parasitic diseases
- Effective against coccidiosis, acute toxoplasmosis, and equine protozoal pyoencephalitis (EPM)
Medchemexpress LLC Fexofenadine | 83799-24-0 | 99.8% | 1 ML
Fexofenadine is an orally active and nonsedative H1 receptor antagonist, suitable for research into allergic rhinitis and chronic idiopathic urticarial. It is provided as a 10 mM solution in DMSO.
- Active and nonsedative H1 receptor antagonist
- Can be used in allergic rhinitis research
- Can be used in chronic idiopathic urticarial research
- Purity of 99.8%
Medchemexpress LLC Tebipenem pivoxil | 161715-24-8 | MFCD17215369 | 99.7% | 1 ML
Tebipenem pivoxil is an orally active antibiotic effective against various pathogenic bacteria. It functions by binding to penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis.
- Orally active antibiotic
- Effective against various pathogenic bacteria
- Inhibits cell wall synthesis
- High purity of 99.7%
Medchemexpress LLC Ganoderic acid A | 81907-62-2 | 516.67 | 25 MG
Ganoderic acid A inhibits the JAK-STAT3 signaling pathway and demonstrates the ability to suppress proliferation, viability, and reactive oxygen species (ROS). It can also enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma at lower doses. It also promotes cisplatin-induced cell death.
- Inhibits JAK-STAT3 signaling pathway.
- Suppresses proliferation and viability.
- Reduces reactive oxygen species (ROS) and DPPH.
- Enhances HLA class II-mediated antigen presentation.
- Promotes cisplatin-induced cell death.
- Induces cell apoptosis in osteosarcoma cells.
- Prolongs survival in EL4 challenged mice and decreases tumor metastasis.
Medchemexpress LLC Ethyl gallate | 831-61-8 | 198.17 | 1 ML
Ethyl gallate is a nonflavonoid phenolic compound and a scavenger of hydrogen peroxide. It has a cytotoxic effect on HL-60 cells, leading to changes in morphology, shrinkage of the cell membrane, development of apoptotic bodies, and decreased cell viability. It is suitable for laboratory research applications.
- Nonflavonoid phenolic compound
- Scavenger of hydrogen peroxide
- Has cytotoxic effect on HL-60 cells
- Leads to changes in morphology, shrinkage of the cell membrane, development of apoptotic bodies, and decreased cell viability
Medchemexpress LLC Propyl gallate | 121-79-9 | 212.20 | 5 G
Propyl gallate is a common food antioxidant that can inhibit the production of acrolein, glyoxal, and methylglyoxal. It exhibits anti-inflammatory, antitumor, and cardioprotective activities.
- Common food antioxidant.
- Can inhibit the production of acrolein, glyoxal, and methylglyoxal.
- Exhibits anti-inflammatory activities.
- Exhibits antitumor activities.
- Exhibits cardioprotective activities.
Medchemexpress LLC Butylparaben | 94-26-8 | 98.9% | 25 G
Butylparaben is an organic compound that serves as an antimicrobial preservative in cosmetics, active molecule suspensions, and as a food flavoring additive. It can also be used in vitro to inhibit porcine oocyte fertilization, cleavage, and blastocyst formation, and in vivo studies have shown no systemic toxicity at certain doses.
- Serves as an antimicrobial preservative
- Can be used in cosmetics and active molecule suspensions
- Functions as a food flavoring additive
- Inhibits porcine oocyte fertilization and development in vitro
- Induces DNA damage, apoptosis, and autophagy in porcine oocytes in vitro
- Shows no systemic toxicity in rats at specific doses in vivo
Medchemexpress LLC Tiamulin | 55297-95-5 | 98.1% | 250 MG
Tiamulin is a diterpenic antibiotic widely used in pigs and poultry to control infectious diseases, particularly airsacculitis caused by Mycoplasma spp. This semisynthetic derivative of Pleuromutilin is highly effective against various Mycoplasma strains, Spirochaetes, and gram-positive bacteria by binding to rRNA and inhibiting protein production. It is less active against gram-negative bacteria. Tiamulin has been shown to be effective in treating avian intestinal spirochaetosis.
- Diterpenic antibiotic for infectious diseases
- Effective against Mycoplasma strains, Spirochaetes, and gram-positive bacteria
- Semisynthetic derivative of Pleuromutilin
- Inhibits protein production by binding to rRNA
- Less active against gram-negative bacteria
- Effective in treating avian intestinal spirochaetosis
Medchemexpress LLC Deacetyl Ganoderic Acid F | 100665-44-9 | 1 MG
Deacetyl Ganoderic Acid F is a 7-anostane triterpenoid from *Ganoderma lucidum*. It is presented as a white to off-white solid with a purity of 98.82%.
- Purity of 98.82%
- Molecular weight: 528.63
- Formula: C30H40O8
- Appearance: White to off-white solid
- Structure classification: Terpenoids, triterpenes
- Initial source: Plants, Polyporaceae
- For research use only
- Store at 4°C, sealed, away from moisture
Sigma Aldrich Fine Chemicals Biosciences fexofenadine Related Compo50MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Medchemexpress LLC Meropenem trihydrate | 119478-56-7 | 99.9% | 437.51 | 25 MG
Meropenem trihydrate is a carbapenem antibiotic with broad-spectrum antibacterial activity. It inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs).
- Intrinsically stable to dehydropeptidase-1 (DHP-1) degradation
- Broad-spectrum in vitro activity against many Gram-positive, Gram-negative, and anaerobic bacteria
- Targets β-lactam
- Active against susceptible and resistant N. gonorrhoeae, H. influenzae, and H. ducreyi