Drug Standards
Medchemexpress LLC Carbidopa | 28860-95-9 | 99.8% | 5 MG
Carbidopa is a peripheral decarboxylase inhibitor used in the research of Parkinson's disease. It acts as a selective aryl hydrocarbon receptor (AhR) modulator and has been shown to inhibit pancreatic cancer cell and tumor growth.
- It is a peripheral decarboxylase inhibitor.
- It can be used for the research of Parkinson's disease.
- It acts as a selective aryl hydrocarbon receptor modulator.
- It inhibits pancreatic cancer cell and tumor growth.
Medchemexpress LLC Iohexol | 66108-95-0 | 99.5% | 1 ML
Iohexol is a non-ionic, water-soluble contrast agent that serves as a reference marker for determining glomerular filtration rate (GFR) at the level of renal function.
- Can be used for contrast in myelography.
- Suitable for computerized tomography (cisternography, ventriculography).
- Applicable for MicroCT imaging.
Medchemexpress LLC Iopamidol | 60166-93-0 | 99.9% | 100 MG
Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) primarily used for various diagnostic applications. It features amide and hydroxyl functionalities, which can be leveraged to generate chemical exchange saturation transfer (CEST) contrast. This product is intended for research use only.
- Nonionic, X-Ray iodinated contrast agent
- Utilized for various diagnostic applications
- Contains amide and hydroxyl functionalities
- Can generate chemical exchange saturation transfer (CEST) contrast
Medchemexpress LLC Ruxolitinib phosphate (INCB018424 phosphate) | 1092939-17-7 | 99.97% | 10 MM * 1 ML
Ruxolitinib phosphate is a potent JAK1/2 inhibitor with IC50s of 3.3 nM for JAK1 and 2.8 nM for JAK2, demonstrating over 130-fold selectivity compared to JAK3. It potently and selectively inhibits JAK2V617F-mediated signaling and proliferation.
- Inhibits the growth of HEL cells with an EC50 of 186 nM.
- Significantly increases apoptosis in the Ba/F3-EpoR-JAK2V617F cell system.
- Inhibits hematopoietic progenitor cell proliferation in primary Myeloproliferative Neoplasm (MPN) patient samples.
Medchemexpress LLC Esomeprazole magnesium (trihydrate) | 217087-09-7 | 99.6% | 767.17 | 1 G
Esomeprazole magnesium trihydrate is a potent and orally active H+, K+-ATPase inhibitor. It has potential for research into upper intestinal disorders and gastroesophageal reflux disease, and acts as an exosome inhibitor by blocking exosome release via the inhibition of V-H+-ATPases.
- Potent and orally active H+, K+-ATPase inhibitor
- Potential for research into upper intestinal disorders
- Potential for gastroesophageal reflux disease research
- Acts as an exosome inhibitor by blocking exosome release
- Inhibits V-H+-ATPases
Medchemexpress LLC Naloxone | 465-65-6 | 99.7% | 327.37 | 50 MG
Naloxone is an antagonist of the Opioid receptor. It alleviates opioid-overdose-induced respiratory depression and may cause pulmonary edema and cardiac arrhythmias. It is for research use only and not sold to patients.
- Alleviates opioid-overdose-induced respiratory depression
- May cause pulmonary edema and cardiac arrhythmias
- For research use only
Medchemexpress LLC (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) | 213779-11-4 | 99.1% | 4309.85 | 10 MG
(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) is a peptide that functions as a parathyroid hormone (PTH) receptor ligand. It is intended for research use only.
- White to off-white solid
- Purity: 99.1%
- CAS Number: 213779-11-4
- Molecular weight: 4309.85
- Molecular formula: C194H303N59O53
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC Doxazosin mesylate | 77883-43-3 | 98.5% | C24H29N5O8S | 100 MG
Doxazosin mesylate is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. It is the mesylate salt form of doxazosin, a long-lasting inhibitor of α1-adrenoceptors. This product is for research use only and is not sold to patients.
- Selectively antagonizes postsynaptic α1-adrenergic receptors
- Long-lasting inhibitor of α1-adrenoceptors
- Used to treat benign prostatic hyperplasia and lower urinary tract symptoms
- May have a direct inhibitory effect on cholesterol synthesis
Medchemexpress LLC Triamcinolone hexacetonide | 5611-51-8 | 532.64 | 10 MG
Triamcinolone hexacetonide is a long-acting steroid commonly used for subacute and chronic inflammatory joint diseases. It is intended for research use only.
- Produces a marked, dose-dependent protective effect in chemically induced articular cartilage damage models.
- Reduces fibrillation and osteophytes in guinea pigs.
- Reduces chondrocyte cloning, cell loss, osteophyte formation, and fibrillation in rabbits.
- Local application can lead to reduced mechanical sensitivity and enhanced regeneration in lingual nerve injury.
- Reformulated iso-osmolar Triamcinolone hexacetonide shows no evidence of deleterious effects on retina function or structure.
Cayman Chemical 2 5dimethyl Celecoxib
An anticancer celecoxib derivative; does not inhibit COX-2 (IC50 = >100 µM); inhibits mPGES-1 in HeLa cells (IC50 = 15.6 µM); reduces PGE2 production in HeLa, A549, and HCA-7 cells (IC50s = 0.64, 0.83, and 3.08 µM, respectively); inhibits proliferation of drug-sensitive RPMI8226 and multidrug-resistant 8226/Dox40 multiple myeloma cells; increases the rate of apoptosis in RPMI8226 and 8226/Dox40 cells at 20 and 30 µM; the antiproliferative effect of 2,5-dimethyl celecoxib is independent of mPGES-1 inhibition
Sigma Aldrich Fine Chemicals Biosciences Chlorpheniramine Related C10MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Apexbio Technology LLC Abacavir sulfate 188062-50-2 10mg
Abacavir sulfate (188062-50-2) is a small-molecule inhibitor targeting HIV reverse transcriptase It is designed to inhibit reverse transcriptase activity thereby blocking viral DNA synthesis Abacavir sulfate exerts its biological activity primarily through intracellular conversion to its active triphosphate form which competes with endogenous substrates to terminate viral nucleic acid polymerization In cell-based studies Abacavir sulfate demonstrates inhibitory activity with an IC50 range of 1 2 to 6 2 M depending on the cell line and experimental protocol Based on these pharmacological properties Abacavir sulfate holds research potential in antiviral research particularly for in vitro HIV infection assays and resistance pathway analyses
Medchemexpress LLC Haloperidol (standard) | 52-86-8 | 99.8% | C₂₁H₂₃ClFNO₂ | 25 MG
Haloperidol (Standard) is the analytical standard of Haloperidol, primarily intended for research and analytical applications. It acts as a potent dopamine D2 receptor antagonist, widely recognized as an antipsychotic.
- Analytical standard for Haloperidol
- Potent dopamine D2 receptor antagonist
- Widely used as an antipsychotic
- Reference standard supplied assay
- Commonly used in HPLC, GC, and MS experiments
Medchemexpress LLC Mavorixafor trihydrochloride | 2309699-17-8 | 99.8% | C21H30Cl3N5 | 1 ML
Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective, and orally available CXCR4 antagonist with an IC50 value of 13 nM against CXCR4 125I-SDF binding. It also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 nM and 9 nM, respectively. This compound can be used for the study of WHIM syndrome.
- Potent, selective, and orally available CXCR4 antagonist
- Inhibits replication of T-tropic HIV-1
- Useful for the study of WHIM syndrome
Medchemexpress LLC Tafamidis meglumine | 951395-08-7 | MFCD28502032 | 99.8% | 503.33 | 1 ML
Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer. It shows comparable potency and efficacy to the mutant homotetramers V30M-TTR, V122I-TTR, and wild type WT-TTR, with EC50s of 2.7-3.2 μM. It inhibits amyloidogenesis. Tafamidis binds selectively and with negative cooperativity (Kds ~2 nM and ~200 nM) to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR. It is for research use only and not sold to patients.
- Potent and selective transthyretin (TTR) stabilizer
- Inhibits amyloidogenesis
- Binds selectively to thyroxine-binding sites
- Kinetically stabilizes TTR
- Comparable potency to mutant and wild type TTR