Ion Chromatography Standards
Apexbio Technology LLC Bifonazole 60628-96-8 1g
Bifonazole (60628-96-8) is a small-molecule inhibitor targeting sterol 14 -demethylase It is designed to block this enzyme thereby impairing ergosterol biosynthesis critical to fungal membrane structure and function Bifonazole exerts its biological activity primarily through inhibition of sterol 14 -demethylase In in vitro studies Bifonazole demonstrates antifungal inhibitory activity with reported IC50 values generally ranging from 0 5 to 4 g/mL depending on fungal species and experimental conditions Based on these pharmacological properties Bifonazole holds research potential in antifungal efficacy evaluation and mechanism-specific assays targeting sterol biosynthesis and membrane disruption
Inorganic Ventures 1000µg/mL POTASSIUM 125mL
Matrix: Nitric Acid (HNO3), Starting Material: KNO3, Analyte: I- 1000 ug/mL.
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Apexbio Technology LLC L-Phenylephrine 59-42-7 1g
L-Phenylephrine (CAS 59-42-7) is a selective agonist of the adrenergic 1A receptor exhibiting a Ki of 1 4 M with markedly lower affinity for 1B (Ki 23 9 M) and 1C (Ki 47 8 M) subtypes In vitro L-Phenylephrine has been shown to reduce apoptosis in neonatal rat cardiomyocytes following hypoxia and serum deprivation and to stimulate proliferation in neural progenitor cells It also increases the cross-sectional area and modulates gene expression in rat neonatal cardiomyocytes In vivo local administration in rats induces cutaneous anesthesia through 1-adrenergic receptor activation and clinical data suggest oral administration reduces nasal airway resistance These properties make L-Phenylephrine a valuable tool for studying 1A-adrenergic receptor-mediated cellular responses
Apexbio Technology LLC Diuron 330-54-1 1g
Diuron is a small-molecule inhibitor targeting electron transport within chloroplasts It is designed to interfere with photosynthesis by suppressing electron transfer thereby affecting cellular energy metabolism via reduced ATP and NADH synthesis Diuron exerts its biological activity primarily through inhibition of electron transfer in chloroplasts In experimental studies in animal models dietary administration of Diuron at elevated concentrations is associated with increased occurrence of urothelial carcinoma Based on these pharmacological properties Diuron holds research potential in studies of photosynthetic biochemical pathways cellular energy regulation and chemical-induced carcinogenesis
Apexbio Technology LLC Ebastine 90729-43-4 1g
Ebastine (CAS 90729-43-4) is an orally active second-generation histamine H1 receptor antagonist It exerts its pharmacological effect by selectively blocking peripheral H1 receptors thereby inhibiting histamine-mediated allergic responses Ebastine is widely employed in biomedical research to investigate the underlying mechanisms of allergic conditions such as allergic rhinitis including symptoms like nasal pruritus sneezing and rhinorrhea It is also utilized in studies of chronic idiopathic urticaria enabling exploration of disease pathology and symptomatic relief in immune and hypersensitivity models
Apexbio Technology LLC Aliskiren 173334-57-1 1g
Aliskiren (CAS 173334-57-1) is a small-molecule inhibitor that targets human renin an aspartyl protease involved in the regulation of the renin angiotensin aldosterone system (RAAS) By directly inhibiting renin activity Aliskiren suppresses the conversion of angiotensinogen to angiotensin I thereby modulating downstream effects on blood pressure regulation It is clinically approved for the management of essential hypertension In biomedical research Aliskiren serves as a tool compound to investigate RAAS-mediated pathways and the physiological consequences of direct renin inhibition in cardiovascular renal and metabolic disease models
Apexbio Technology LLC Ibuprofen 15687-27-1 1g
Ibuprofen (CAS 15687-27-1) is a small-molecule inhibitor targeting cyclooxygenase enzymes COX-1 and COX-2 It is designed to inhibit prostaglandin prostacyclin and thromboxane biosynthesis thereby regulating inflammation and pain pathways Ibuprofen exerts its biological activity primarily through COX enzyme inhibition In cell-based studies ibuprofen demonstrates anti-proliferative activity with an IC50 value of approximately 12 M for COX-1 and 80 M for COX-2 in relevant experimental models including human colon carcinoma HCT-116 cells Based on these pharmacological properties ibuprofen holds research potential in inflammation studies oncology lipid metabolism and neurobiology
Apexbio Technology LLC Progesterone 57-83-0 1g
Progesterone (57-83-0) is a steroid hormone that modulates reproductive processes by specifically interacting with its nuclear receptors It is designed to regulate embryo implantation and endometrial physiology thereby influencing estrogenic signaling and target gene expression in reproductive tissues Progesterone exerts its biological activity primarily through attenuation of estrogenic signaling affecting genes such as Egr1 In in vitro studies progesterone demonstrates the ability to restrict cell proliferation pathways in melanoma models including B16F10 mouse cells and BLM human cell lines Additionally progesterone regulates mammary carcinoma progression via RANKL-dependent activation of signaling components such as GLI-1 Based on these pharmacological properties progesterone holds research potential in studies of hormonal regulation reproductive biology cancer progression and neuroprotection
THERMO SCI 3P AIG PARTS & ACCESSORIES SULFATE STD 1000MG/L 100ML
NC1145535 SULFATE STD 1000MG/L 100ML
Apexbio Technology LLC Acetylcholine Chloride 60-31-1 1g
Acetylcholine chloride is an endogenous cholinergic agonist targeting nicotinic and muscarinic acetylcholine receptors It is designed to modulate cholinergic neurotransmission thereby regulating muscular contraction autonomic signaling and neuroendocrine responses Acetylcholine chloride exerts its biological activity primarily through binding and activating specific cholinergic receptors In experimental studies acetylcholine chloride demonstrates receptor activation properties and is frequently utilized in vitro to investigate receptor-ligand interactions synaptic transmission and neural transduction pathways Based on these pharmacological properties acetylcholine chloride holds research potential in neuroscience and pharmacological studies focused on cholinergic signaling and receptor characterization