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Filtered Search Results
eMolecules Pharmablock / 4-methoxypyridine-3-carboxylic acid / 25mg / 788564341 / PBU2965 / 0.000 / 10177-31-8 / MFCD04115724 / 153.137 / C7H7NO3
Pharmablock / 4-methoxypyridine-3-carboxylic acid / 25mg / 788564341 / PBU2965 / 0.000 / 10177-31-8 / MFCD04115724 / 153.137 / C7H7NO3
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Medchemexpress LLC 11-Oxomogroside IIIE | 2096516-68-4 | 10 MG
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11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Lo Han Kuo (Siraitia grosvenori). It is for research use only.
- Purity: 99.69%
- Molecular weight: 961.14
- Formula: C48H80O19
- Appearance: Solid
- Color: White to off-white
- Structure classification: Terpenoids, triterpenes
- Initial source: Plants, cucurbitaceae, Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang
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Medchemexpress LLC AMY-101 | 1427001-89-5 | 99.86% | 1789.09 | 10 MG
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AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 with a KD of 0.5 nM. It has been shown to inhibit naturally occurring periodontitis in non-human primates (NHPs) and exhibits favorable anti-inflammatory activity in models of COVID-19 severe pneumonia with systemic hyper-inflammation.
- Inhibits central complement component C3
- Improves periodontal condition in NHPs
- Induces a long-lasting anti-inflammatory effect
- Attenuates fibrosis and infiltration of inflammatory cells in UUO-induced renal fibrosis
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Medchemexpress LLC P-gp inhibitor 1 | 2050747-49-2 | 98.8% | 517.62 g·mol⁻¹ | C32H31N5O2 | 25 MG
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P-gp inhibitor 1 is a small-molecule inhibitor that reverses P-glycoprotein (ABCB1/MDR1)-mediated multidrug resistance. Supplied as a purified solid for research use, it is intended for use in in vitro transporter inhibition assays, drug-drug interaction studies, and cellular models of chemoresistance. Not for human or veterinary use.
- Reverses P-glycoprotein-mediated multidrug resistance in cellular assays.
- High purity suitable for biochemical and cellular studies.
- Soluble in common organic solvents for assay preparation.
- Useful for transporter inhibition and drug-interaction profiling.
- Supplied as a measured mass for reproducible dosing in experiments.
- Intended for research use only.
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Medchemexpress LLC TL13-112 | 2229037-19-6 | MFCD12922943 | 98.0% | 1002.57 g/mol | C49H60ClN9O10S | 100MG
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TL13-112 is a potent, selective anaplastic lymphoma kinase (ALK) PROTAC degrader supplied for research use. It inhibits ALK activity and induces ALK degradation in cellular assays; analytical data, certificates, and stability information are provided by the supplier.
- Potent ALK degrader with reported ALK IC50 of 0.14 nM.
- Molecular weight 1002.57 g/mol and formula C49H60ClN9O10S.
- Purity reported as 98.0% with supporting analytical data.
- Soluble in DMSO at approximately 100 mg/mL.
- Provided as a solid with recommended storage conditions for powder and in solvent.
- Intended for biochemical and cell-based research applications only.
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STA PHARMACEUTICAL US LLC Fmoc-L-Orn(Dnp)-OH | 25 g | CAS 252049-04-0 | MDL MFCD02259486
Fmoc-L-Orn(Dnp)-OH is a Amino Acid reagent (Subcategory: Lys) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 252049-04-0
- MDL: MFCD02259486
- InChIKey: QIVVRAUNWOIMQK-QHCPKHFHSA-N
- Molecular Weight: 520.498
- Molecular Formula: C26H24N4O8
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((2,4-dinitrophenyl)amino)pentanoic acid
- SMILES: O=[N+](C1=CC([N+]([O-])=O)=C(NCCC[C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)C(O)=O)C=C1)[O-]
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Medchemexpress LLC Pennogenin | 507-89-1 | 5 MG
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Pennogenin is a bioactive component isolated from T. govanianum rhizomes. It exhibits a significant in vitro inhibitory effect on the release of Reactive Oxygen Species (ROS).
- Bioactive component
- Isolated from T. govanianum rhizomes
- Exhibits significant in vitro inhibitory effect on the release of reactive oxygen species (ROS)
- Significant level of oxidative burst suppressive activity
- Shows a significant in vitro inhibitory effect on the release of ROS from whole blood, with an IC50 of 5.0 μg/mL
- Purity: 99.90%
- Available in solid form, white to off-white color
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Medchemexpress LLC Corynoline | 18797-79-0 | 98.8% | 367.40 g·mol⁻¹ | C21H21NO5 | 10 MG
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Corynoline is a natural isoquinoline alkaloid used as a research reagent. It functions as a reversible, noncompetitive acetylcholinesterase (AChE) inhibitor (IC50 = 30.6 μM) and has reported anti-inflammatory activity through activation of the Nrf2 pathway. The compound is supplied as a high-purity solid for laboratory studies and is intended for research use only.
- Reversible, noncompetitive acetylcholinesterase inhibitor (IC50 = 30.6 μM).
- Activates Nrf2 and exhibits anti-inflammatory activity.
- High purity suitable for analytical and biological research.
- Supplied as a 10 mg solid for laboratory use.
- Intended for research use only; not for human or veterinary use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / (S)-Indoline-2-carboxylic acid / 1g / 490558368 / A375797 / / 79815-20-6 / MFCD00070578 / 163.176 / C9H9NO2
Ambeed / (S)-Indoline-2-carboxylic acid / 1g / 490558368 / A375797 / / 79815-20-6 / MFCD00070578 / 163.176 / C9H9NO2
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![Medchemexpress LLC 3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-dimethylpropan-1-amine | 1219962-49-8 | 98.8% | 397.519 g·mol⁻¹ | C23H31N3O3 | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236031.png-250.jpg)
Medchemexpress LLC 3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-dimethylpropan-1-amine | 1219962-49-8 | 98.8% | 397.519 g·mol⁻¹ | C23H31N3O3 | 25MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AT791 is a small-molecule, orally bioavailable inhibitor of Toll-like receptors TLR7 and TLR9. It blocks DNA-TLR9 interaction in vitro and suppresses cytokine responses such as IL-6 and type I interferon in human and mouse cells, making it suitable for immunology and autoimmune research.
- Orally bioavailable small-molecule inhibitor of TLR7 and TLR9.
- Blocks DNA-TLR9 interaction and inhibits TLR-mediated signaling in vitro.
- Potent activity against TLR9 (low-nanomolar IC50) and weaker activity against TLR7.
- High-purity solid with good solubility in DMSO (~10 mM) for assay preparation.
- Appropriate for cellular and in vivo studies of TLR-driven immune responses.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / Indane-5-carboxylic Acid / 100mg / 589771025 / A347938 / / 65898-38-6 / MFCD04038659 / 162.188 / C10H10O2
Ambeed / Indane-5-carboxylic Acid / 100mg / 589771025 / A347938 / / 65898-38-6 / MFCD04038659 / 162.188 / C10H10O2
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / 2-(4-Nitrophenyl)-2-oxoacetic acid / 250mg / 525027051 / A125734 / / 14922-36-2 / MFCD00051744 / 195.130 / C8H5NO5
Ambeed / 2-(4-Nitrophenyl)-2-oxoacetic acid / 250mg / 525027051 / A125734 / / 14922-36-2 / MFCD00051744 / 195.130 / C8H5NO5
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Pseudolaric Acid B | 82508-31-4 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Pseudolaric Acid B is an orally active diterpene acid that exhibits anti-fungal, anti-fertility, anti-angiogenesis, and anticancer activities. It can induce tumor cell apoptosis and autophagy, inhibit hepatitis B virus (HBV) secretion, and has an immunosuppressive effect by selectively inhibiting T lymphocyte proliferation and IL-2 production.
- Induces tumor cell apoptosis
- Induces autophagy
- Inhibits hepatitis B virus (HBV) secretion
- Has immunosuppressive effect
- Selectively inhibits the proliferation of T lymphocytes
- Selectively inhibits the production of IL-2
- Exhibits anti-fungal activity
- Exhibits anti-fertility activity
- Exhibits anti-angiogenesis activity
- Exhibits anticancer activity
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences Hexachlorophene United States Pharmacopeia (USP) Reference Standard | 70-30-4 | MFCD00002171 | 500MG
Hexachlorophene United States Pharmacopeia (USP) Reference Standard | Mol Wt: 406.9 | 70-30-4 | MFCD00002171 | 500MG
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Medchemexpress LLC Enzalutamide-based VHL-recruiting androgen receptor degrader (ARCC-4) | 1973403-00-7 | MFCD32858266 | 99.9% | C53H56F3N7O7S2 | 10MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A potent proteolysis-targeting chimera (PROTAC) small molecule that induces targeted proteasomal degradation of the androgen receptor (AR). It demonstrates low-nanomolar degradation activity in cellular assays and is used to probe AR signaling and prostate cancer biology. Molecular formula C53H56F3N7O7S2; molecular weight 1024.18 Da.
- Low-nanomolar potency for androgen receptor degradation.
- Mechanism recruits VHL E3 ligase to promote proteasomal degradation.
- Effective against wild-type and clinically relevant AR mutants in cell models.
- High purity suitable for in vitro research applications.
- Available in multiple small-scale pack sizes and as a DMSO solution for convenience.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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