Acetylides
Medchemexpress LLC Propargyl-PEG8-OH | 1351556-81-4 | 100 MG
Propargyl-PEG8-OH is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This click chemistry reagent contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Propargyl-PEG8-Boc | 2055014-96-3 | 100 MG
Propargyl-PEG8-Boc is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This click chemistry reagent features an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules containing Azide groups. PROTACs are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC)
- Reacts with azide-containing molecules
Medchemexpress LLC Propargyl-PEG8-OH | 1351556-81-4 | 5 G
Propargyl-PEG8-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Molecular weight: 408.48
- Formula: C19H36O9
- Relevant for cancer and cancer targeted therapy
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 25 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 25 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Sigma Aldrich Fine Chemicals Biosciences Selegiline Related Compound D United States Pharmacopeia (USP) Reference Standard | 115586-38-4 | MFCD00272656 | 15MG
Selegiline Related Compound D United States Pharmacopeia (USP) Reference Standard | Mol Wt: 209.72 | 115586-38-4 | MFCD00272656 | 15MG
Medchemexpress LLC Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 1,1-dimethylethyl ester | 1807503-80-5 | 95.0% | 250 MG
This compound is a polyethylene glycol (PEG)-based PROTAC linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It acts as a click chemistry reagent due to its alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.
- Application: Can be employed in the synthesis of PROTACs.
- Characteristics: It contains an alkyne group and can participate in copper-catalyzed azide-alkyne cycloaddition.
eMolecules Ambeed / N-Boc-Propargylamine / 1g / 552613515 / A171481 / / 92136-39-5 / MFCD07367245 / 155.197 / C8H13NO2
Ambeed / N-Boc-Propargylamine / 1g / 552613515 / A171481 / / 92136-39-5 / MFCD07367245 / 155.197 / C8H13NO2
Medchemexpress LLC Propargyl-PEG8-Boc | 2055014-96-3 | 250 MG
Propargyl-PEG8-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 1 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 60 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 63 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | 302.36 | 250 MG
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent containing an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
- Utilizes two different ligands connected by a linker; one ligand for an E3 ubiquitin ligase and another for the target protein
- Employs the intracellular ubiquitin-proteasome system to selectively degrade target proteins
eMolecules (5-Bromo-2-(trifluoromethoxy)phenyl)boronic acid | 1072951-56-4 | MFCD11504857 | 1g
Ambeed | (5-Bromo-2-(trifluoromethoxy)phenyl)boronic acid | 1g | 600846045 | A705919 | | 1072951-56-4 | MFCD11504857 | 284.820 | C7H5BBrF3O3
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Sigma Aldrich Fine Chemicals Biosciences 3-Chloro-3-methyl-1-butyne 97% | 1111-97-3 | MFCD00190221 | 25G
3-Chloro-3-methyl-1-butyne 97% | Purity: 97% | Mol Wt: 102.56 | 1111-97-3 | MFCD00190221 | 25G