Acetylides
Medchemexpress LLC Propargyl-PEG7-Boc | 1818294-29-9 | >95% | 1 G
Propargyl-PEG7-Boc is a polyethylene glycol (PEG)-based PROTAC linker. It can be used in the synthesis of a series of PROTACs.
- Polyethylene glycol (PEG)-based PROTAC linker
- Used in the synthesis of PROTACs
- Purity >95%
- Soluble in DCM, DMF, DMSO
- Appearance: Pale yellow or colorless oily liquid
Medchemexpress LLC Propargyl-PEG5-NHS ester | 1393330-40-9 | 98.0% | 1 G
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker primarily used in the synthesis of PROTACs. It also functions as a cleavable ADC linker, crucial for synthesizing antibody-drug conjugates (ADCs).
- Functions as a cleavable ADC linker
- Used in the synthesis of antibody-drug conjugates (ADCs)
- Click chemistry reagent
- Contains an alkyne group
- Engages in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | MFCD28334507 | >98.0% | 407.50 g/mol | C19H37NO8 | 10 MG
Propargyl-PEG8-NH2 is an alkyne-terminated polyethylene glycol (PEG8) amine linker used for bioconjugation and linker synthesis. It provides a terminal alkyne for click chemistry and a primary amine for further derivatization, with a PEG8 spacer to improve solubility and spacing between conjugated moieties.
- Provides a terminal alkyne group for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Contains a primary amine for amide formation and further functionalization.
- PEG8 spacer improves solubility and reduces steric hindrance.
- High chemical purity suitable for research applications.
- Colorless to light yellow liquid, convenient for solution-phase coupling reactions.
- Commonly used in PROTAC, ADC, and general bioconjugation workflows.
Enzo Life Sciences R(-)-Deprenyl. HCl (100mg). CAS: 14611-52-0
Deprenyl inhibits apoptosis and displays neuroprotective effects in a variety of in vitro and in vivo systems. In vivo it rescues nigral dopaminergic neurons after systemic MPTP treatment. In vitro it rescues PC12 cells from apoptotic cell death induced by trophic withdrawal. The putative target responsible for the anti-apoptotic effects is glyceraldehyde-3-phosphate dehydrogenase. Deprenyl also inhibits monoamine oxidase-B, which is not involved in its anti-apoptotic mechanism. Parkinson’s disease therapeutic. Alternative name: Selegiline hydrochloride. Purity: ≥98% (HPLC). Solubility: Soluble in water. Long Term Storage: Ambient.
eMolecules Ambeed / Methyl 2-ethynylbenzoate / 250mg / 552687157 / A272766 / / 33577-99-0 / MFCD12547057 / 160.172 / C10H8O2
Ambeed / Methyl 2-ethynylbenzoate / 250mg / 552687157 / A272766 / / 33577-99-0 / MFCD12547057 / 160.172 / C10H8O2
Medchemexpress LLC Fmoc-amino-PEG3-CH2COOH | 139338-72-0 | 99.8% | 429.46 | 1 G
Fmoc-amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
Medchemexpress LLC 4-Ethynylaniline | 14235-81-5 | 117.15 | 5 G
4-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It is a click chemistry reagent containing an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Used in click chemistry
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Biochemical assay reagent
Medchemexpress LLC Bis-propargyl-PEG8 25mg | 1092554-87-4 | 446.53 | C22H38O9 | 25 MG
Bis-propargyl-PEG8 is a PEG-based bifunctional linker bearing terminal propargyl (alkyne) groups. It is used in click chemistry (copper-catalyzed azide-alkyne cycloaddition) and for assembling PROTACs and other bioconjugates in research settings.
- Contains terminal alkyne groups suitable for CuAAC reactions.
- PEG8 spacer provides water solubility and flexible linkage.
- Bifunctional ends enable conjugation to two partners.
- Available in research-scale package sizes for synthesis workflows.
- Compatible with common organic synthesis and bioconjugation methods.
eMolecules 3-METHYL-4-(TRIFLUOROMETHOXY)ANILINE | 183945-52-0 | MFCD18399693 | 1g
AstaTech | 3-METHYL-4-(TRIFLUOROMETHOXY)ANILINE | 1g | 248486670 | CL9249 | 95.000 | 183945-52-0 | MFCD18399693 | 191.153 | C8H8F3NO
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eMolecules 3-Butoxy-5-(trifluoromethoxy)phenylboronic acid | 1256345-96-6 | MFCD16036112 | 1g
Combi-Blocks | 3-Butoxy-5-(trifluoromethoxy)phenylboronic acid | 1g | 117524581 | BB-6361 | 97.000 | 1256345-96-6 | MFCD16036112 | 278.030 | C11H14BF3O4
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Medchemexpress LLC Bis-propargyl-PEG8 50mg | 1092554-87-4 | 50 MG
Bis-propargyl-PEG8 is a polyethylene glycol-based bifunctional linker bearing terminal propargyl (alkyne) groups. It functions as a flexible PEG8 spacer for click-chemistry conjugations, PROTAC construction, and other bioconjugation applications.
- Contains two terminal propargyl (alkyne) groups for CuAAC click reactions.
- PEG8 spacer provides flexibility and increased hydrophilicity.
- Applicable to PROTAC and ADC linker synthesis and general bioconjugation workflows.
- Supplied as a solid, commonly offered in milligram quantities such as 50 mg.
- Characterized by chemical formula C22H38O9 and molecular weight 446.53 g·mol-1.
eMolecules 3-Chloro-4-(trifluoromethoxy)phenol | 1000339-94-5 | MFCD04972754 | 1g
Combi-Blocks | 3-Chloro-4-(trifluoromethoxy)phenol | 1g | 205391475 | OR-6397 | 97.000 | 1000339-94-5 | MFCD04972754 | 212.550 | C7H4ClF3O2
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