Acetylides
Medchemexpress LLC Arecaidine propargyl ester hydrobromide | 116511-28-5 | MFCD00078566 | 99.5% | 260.13 g/mol | C10H14BrNO2 | 5 MG
Arecaidine propargyl ester hydrobromide is a research-grade small molecule that acts as an agonist of M2 muscarinic acetylcholine receptors and has been reported to induce apoptosis, increase reactive oxygen species, and cause G2/M cell-cycle arrest in certain tumor cell models.
- Purity: 99.5%.
- Appearance: white to off-white solid.
- Molecular weight: 260.13 g/mol.
- Chemical formula: C10H14BrNO2.
- Biological activity: M2 muscarinic receptor agonist; reported inhibition of tumor cell proliferation.
- Storage: store sealed at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Pack sizes: available in 1 mg, 5 mg, and 10 mg.
Medchemexpress LLC Propargyl-PEG4-GGFG-DXd | 2762518-94-3 | MFCD01346226 | 100.0% | 1083.12 | C54H63FN8O15 | 100 MG
Propargyl-PEG4-GGFG-DXd is a drug-linker conjugate for antibody-drug conjugates (ADCs) that links an ADC linker to the DNA topoisomerase I inhibitor DXd and provides a propargyl handle for bioorthogonal conjugation.
- Molecular formula: C54H63FN8O15
- Molecular weight: 1083.12
- Cas number: 2762518-94-3
- Purity: 99.99%
- Appearance: solid, off-white to light yellow
- Storage: 4°C sealed, away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month
- Package size: available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg; larger sizes available by quote
Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | 98.0% | 187.24 | 100 MG
Propargyl-PEG3-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent that contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
eMolecules 4-Fluoro-2-(trifluoromethoxy)-DL-phenylalanine | 1435806-18-0 | MFCD19687192 | 1g
Apollo Scientific | 4-Fluoro-2-(trifluoromethoxy)-DL-phenylalanine | 1g | 562460231 | PC302877 | | 1435806-18-0 | MFCD19687192 | 267.180 | C10H9F4NO3
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Medchemexpress LLC Propargyl-PEG6-alcohol | 944560-99-0 | 97.0% | 1 G
Propargyl-PEG6-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Used in the synthesis of proteolysis targeting chimeras (PROTACs)
- Contains an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins
![Medchemexpress LLC Ethanamine, 2-[2-(2-propyn-1-yloxy)ethoxy]- | 944561-44-8 | MFCD19160595 | 99.6% | 143.18 g/mol | C7H13NO2 | 100 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202861.png-250.jpg)
Medchemexpress LLC Ethanamine, 2-[2-(2-propyn-1-yloxy)ethoxy]- | 944561-44-8 | MFCD19160595 | 99.6% | 143.18 g/mol | C7H13NO2 | 100 G
Propargyl-PEG2-amine is a PEG-based bifunctional linker that contains a terminal propargyl (alkyne) group and a primary amine, designed for conjugation chemistry and synthetic applications such as antibody-drug conjugate (ADC) formation, PROTAC assembly, and click chemistry.
- PEG-2 spacer with terminal propargyl group
- Primary amine functional group for conjugation
- High purity suitable for synthesis (99.6%)
- Colorless to light yellow liquid; density 0.992 ± 0.06 g/cm3
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC)
Medchemexpress LLC Propargyl-PEG1-NHS ester | 1174157-65-3 | 98.9% | 225.20 g/mol | C10H11NO5 | 1 G
Propargyl-PEG1-NHS ester is a small polyethylene glycol (PEG1) linker bearing an N-hydroxysuccinimide (NHS) ester and a terminal propargyl (alkyne) group. It is designed to derivatize primary amines via NHS chemistry and to introduce an alkyne handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC) click reactions, enabling bioconjugation and linker construction.
- Reactive NHS ester for conjugation to primary amines.
- Terminal alkyne (propargyl) enables CuAAC click chemistry.
- Small PEG1 spacer reduces steric hindrance and improves solubility.
- Typical assay purity reported around 98.9%.
- Stable when stored at -20°C in pure form for extended periods.
Medchemexpress LLC N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) | 2112732-01-9 | > 96% | 519.58 | 250 MG
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Alkyne group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Allows copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC Propargyl-PEG8-OH | 1351556-81-4 | 5 G
Propargyl-PEG8-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Molecular weight: 408.48
- Formula: C19H36O9
- Relevant for cancer and cancer targeted therapy
(C)C#C | 5g | 335349791](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000225586.jpg-250.jpg)
eMolecules 1066-54-2 | Trimethylsilylacetylene | Combi-Blocks | MFCD00008569 | 98.220 | C5H10Si | 95.000 | C[Si](C)(C)C#C | 5g | 335349791
Trimethylsilylacetylene | Combi-Blocks | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 95.000 | C[Si](C)(C)C#C | 5g | 335349791
eMolecules 1066-54-2 | Trimethylsilylacetylene | Combi-Blocks | MFCD00008569 | 98.220 | C5H10Si | 95.000 | C[Si](C)(C)C#C | 25g | 267169361
Trimethylsilylacetylene | Combi-Blocks | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 95.000 | C[Si](C)(C)C#C | 25g | 267169361
Chemscene ChemScene | 4-Chloro-2-(trifluoromethoxy)aniline | 10G | CS-W015037 | 0.98 | 175205-77-3| MFCD00153102 | 211.57
ChemScene | 4-Chloro-2-(trifluoromethoxy)aniline | 10G | CS-W015037 | 0.98 | 175205-77-3| MFCD00153102 | 211.57
eMolecules 1240257-07-1 | 2-Fluoro-4-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | MFCD16652441 | 210.128 | C8H6F4O2 | 98.000 | OCc1ccc(OC(F)(F)F)cc1F | 1g | 562454556
2-Fluoro-4-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | 1240257-07-1 | MFCD16652441 | 210.128 | C8H6F4O2 | 98.000 | OCc1ccc(OC(F)(F)F)cc1F | 1g | 562454556
eMolecules 764-37-4 | (E)-Pent-3-en-1-ol | Combi-Blocks, Inc. | MFCD07636756 | 86.134 | C5H10O | 95.000 | C\C=C\CCO | 10g | 854189544
(E)-Pent-3-en-1-ol | Combi-Blocks, Inc. | 764-37-4 | MFCD07636756 | 86.134 | C5H10O | 95.000 | C\C=C\CCO | 10g | 854189544