Hydrobromides
Medchemexpress LLC Remodelin hydrobromide | 1622921-15-6 | 99.6% | 363.28 | 50 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It works by inhibiting NAT10 activity, which in turn slows down DNA replication and suppresses the growth of prostate cancer cells. This compound has been shown to inhibit the growth of both prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, it enhances the healthspan in a mouse model of Hutchinson-Gilford progeria syndrome (HGPS).
- Orally active and selective inhibitor.
- Inhibits NAT10 activity.
- Slows DNA replication.
- Suppresses growth of prostate cancer cells.
- Inhibits growth of hepatocellular carcinoma in xenograft models.
- Enhances healthspan in a mouse model of HGPS.
Medchemexpress LLC Fatostatin hydrobromide | 298197-04-3 | MFCD00760867 | 99.52% | C18H19BrN2S | 25 MG
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation. It impairs the activation of SREBP-1 and SREBP-2 by binding to SCAP (SREBP cleavage-activating protein), which inhibits the ER-Golgi translocation of SREBPs. This action leads to a decrease in the transcription of lipogenic genes in cells.
- Specific inhibitor of SREBP activation.
- Impairs activation of SREBP-1 and SREBP-2.
- Inhibits ER-Golgi translocation of SREBPs.
- Decreases transcription of lipogenic genes.
- Exhibits antitumor properties.
- Lowers hyperglycemia in ob/ob mice.
Medchemexpress LLC Galanthamine hydrobromide (Galantamine hydrobromide) | 1953-04-4 | 99.9% | C17H22BrNO3 | 500 MG
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is primarily developed for research into Alzheimer's disease (AD).
- Selective, reversible, competitive alkaloid AChE inhibitor
- Potent allosteric potentiating ligand of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs)
- Developed for Alzheimer's disease (AD) research
- IC50 of 0.35 μM for AChE
eMolecules 849928-26-3 | 1-Boc-3-Bromopiperidine | ChemScene | MFCD07779077 | 264.163 | C10H18BrNO2 | 95.000 | CC(C)(C)OC(=O)N1CCCC(Br)C1 | 25g | 859848138
1-Boc-3-Bromopiperidine | ChemScene | 849928-26-3 | MFCD07779077 | 264.163 | C10H18BrNO2 | 95.000 | CC(C)(C)OC(=O)N1CCCC(Br)C1 | 25g | 859848138