Hydrobromides
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g/mol | C6H13Br2N3S | 1 ML
Amthamine dihydrobromide is a histamine receptor agonist supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid material for laboratory use. It is used in receptor pharmacology and hepatotoxicity research to probe histamine-mediated biological responses.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- High purity (99.6%) suitable for biological assays.
- Also available as solid in multiple vial sizes for synthesis or formulation.
- CAS number 142457-00-9 for unambiguous identification.
- Useful for histamine receptor pharmacology and hepatotoxicity studies.
Medchemexpress LLC Guvacoline hydrobrom 25mg | 17210-51-4 | 25 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid found in Areca triandra. It is used as a research reagent and functions as a weak full agonist of atrial and ileal muscarinic acetylcholine receptors (mAChR).
- Acts as a weak full agonist of atrial and ileal muscarinic receptors.
- White to off-white solid physical form.
- Molecular formula C7H12BrNO2 and molecular weight 222.08.
- Purity typically around 96.09% by HPLC.
- Store sealed at 4°C and protect from moisture and light; in solution store at -80°C for long-term.
- Supplied in small milligram pack sizes for laboratory research.
Apexbio Technology LLC Imetit dihydrobromide 32385-58-3 5mg
Imetit dihydrobromide (CAS 32385-58-3) is a potent high-affinity agonist of histamine H3 and H4 receptors demonstrating Ki values of 0 3 nM and 2 7 nM respectively Functionally it replicates histaminergic effects by inducing morphological changes in eosinophils with an EC50 of 25 nM Owing to its selective receptor activity Imetit dihydrobromide is widely employed in studies investigating allergic inflammatory processes including asthma as well as in research focused on central nervous system physiology and histamine-related pathways
Apexbio Technology LLC A 61603 hydrobromide 107756-30-9 5mg
A 61603 hydrobromide (CAS 107756-30-9) is a potent and highly selective agonist of the 1A-adrenergic receptor one of the 1-adrenergic receptor subtypes involved in cellular growth and proliferation Compared to its activity at 1B- and 1D-adrenergic receptors A 61603 demonstrates approximately 35-fold higher potency for 1A-AR In cellular assays it robustly induces phosphoinositide hydrolysis in 1A-AR-expressing fibroblasts (pEC50 8 24) and in neonatal rat cardiomyocytes it increases calcium transient frequency in a dose-dependent manner (EC50 6 9 nM) In vascular models A 61603 markedly elevates perfusion pressure demonstrating significantly greater efficacy than noradrenaline This compound serves as a valuable tool for delineating 1A-AR-mediated signaling and vascular regulation
eMolecules ChemScene N-Boc-4-bromopiperidine 25g 536904869 CS-W001478 180695-79-8 MFCD04115039 264.163 C10H18BrNO2
ChemScene N-Boc-4-bromopiperidine 25g 536904869 CS-W001478 180695-79-8 MFCD04115039 264.163 C10H18BrNO2
Medchemexpress LLC CCT031374 hydrobromide | 1219184-91-4 | MFCD06737234 | 98.1% | 434.33 g·mol⁻¹ | C23H20BrN3O | 5 MG
CCT031374 hydrobromide is the hydrobromide salt of a small-molecule β-catenin/TCF signaling inhibitor supplied for research use only. It is provided as an off-white to light yellow solid with high chemical purity and is intended for pathway inhibition, cell signaling assays, and preclinical studies.
- β-catenin/TCF signaling inhibitor
- High purity (98.1%)
- Molecular weight 434.33 g·mol⁻¹
- Off-white to light yellow solid form
- Available in milligram-scale packages for research use
- Intended for in vitro and in vivo research applications
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.
eMolecules Synthonix 3-Bromopiperidine-2 6-dione 250mg 534611341 B41113 0 000 62595-74-8 MFCD11053059 192 012 C5H6BrNO2
Synthonix 3-Bromopiperidine-2 6-dione 250mg 534611341 B41113 0 000 62595-74-8 MFCD11053059 192 012 C5H6BrNO2