Hydrobromides
Medchemexpress LLC Oxidopamine hydrobromide | 636-00-0 | 99.42% | 100 MG
Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine. It is a widely used neurotoxin that selectively destroys dopaminergic neurons. It promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrobromide can be used for the research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Antagonist of the neurotransmitter dopamine.
- Widely used neurotoxin.
- Selectively destroys dopaminergic neurons.
- Promotes COX-2 activation.
- Leads to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Used for research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
TARGETMOL CHEMICALS INC Clobenpropit dihydrobromide
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07) Purity 99.48%
Apexbio Technology LLC Scopolamine hydrobromide 114-49-8 500mg
Scopolamine hydrobromide (114-49-8) is a small-molecule antagonist targeting muscarinic acetylcholine receptors and serotonin 5-HT3 receptors It is designed to reversibly block these receptors thereby modulating cholinergic and serotonergic signaling pathways Scopolamine hydrobromide exerts its biological activity primarily through reversible antagonism of muscarinic receptors and inhibition of serotonin 5-HT3 receptor responses In receptor binding studies Scopolamine hydrobromide demonstrates antagonistic activity with reported IC50 values generally ranging from nanomolar to micromolar concentrations depending on the receptor subtype and experimental conditions Based on these pharmacological properties Scopolamine hydrobromide holds research potential in studies of neurotransmission cholinergic signaling gastrointestinal motility assays cognitive impairment models and emesis reflex investigations