Hydrobromides
Medchemexpress LLC Rociletinib hydrobromide | 1446700-26-0 | MFCD28386290 | 98.0% | 636.46 g/mol | C27H29BrF3N7O3 | 10 MG
Rociletinib hydrobromide is the hydrobromide salt of rociletinib, an orally active kinase inhibitor selective for mutant forms of the epidermal growth factor receptor (EGFR) including T790M. It is supplied as a solid research reagent for biochemical, cellular, and analytical studies.
- Hydrobromide salt of rociletinib.
- Selective inhibitor of mutant EGFR, including T790M.
- Intended for research and analytical applications.
- Purity 98.04% (HPLC).
- Molecular weight 636.46 g/mol.
- CAS number 1446700-26-0.
- Store sealed, away from moisture; in solvent: -80°C (6 months) or -20°C (1 month).
eMolecules Ambeed 3-Bromopiperidine-2 6-dione 250mg 506392068 A875928 0 000 62595-74-8 MFCD11053059 192 012 C5H6BrNO2
Ambeed 3-Bromopiperidine-2 6-dione 250mg 506392068 A875928 0 000 62595-74-8 MFCD11053059 192 012 C5H6BrNO2
Apexbio Technology LLC Teneligliptin hydrobromide 906093-29-6 10mM (in 1mL DMSO)
Teneligliptin hydrobromide (CAS 906093-29-6) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor exhibiting competitive inhibition of human and rat plasma DPP-4 with an IC50 of approximately 1 nM DPP-4 also known as CD26 is a cell surface protease involved in immunoregulation signal transduction and apoptosis In vitro Teneligliptin hydrobromide reduces reactive oxygen species and modulates cell cycle and apoptotic gene expression in human endothelial cells exposed to high glucose In vivo it ameliorates hepatic steatosis and metabolic disturbances in murine models partly through activation of hepatic AMPK This compound supports studies of metabolic oxidative and inflammatory pathways