Hydrochlorides
Medchemexpress LLC Erlotinib (hydrochloride) | 183319-69-9 | 99.9% | 50 MG
Erlotinib hydrochloride is a small-molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor supplied as the hydrochloride salt for research use in biochemical and cell-based assays.
- Inhibits EGFR tyrosine kinase with low-nanomolar potency.
- Supplied as a solid hydrochloride salt suitable for analytical and biological studies.
- High purity (99.9% by LCMS) for reliable experimental results.
- Soluble in DMSO for preparation of stock solutions.
- Commonly used in kinase assays and cellular signaling research.
Medchemexpress LLC Tirofiban hydrochloride monohydrate | 150915-40-5 | 99.9% | 495.07 | 50 MG
Tirofiban hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and possesses antithrombotic activity. It induces proliferation and migration of endothelial cells by stimulating VEGF production, and can significantly reduce myocardial no-reflow and ischemia-reperfusion injury.
- Inhibits fibrinogen binding to platelet integrin receptor (Gp IIb/IIIa).
- Possesses antithrombotic activity.
- Induces proliferation and migration of endothelial cells.
- Reduces myocardial no-reflow and ischemia-reperfusion injury.
- Increases contraction force and improves heart function in rats.
- Demonstrates anticoagulant effect after microvascular anastomosis.
Medchemexpress LLC Carteolol hydrochloride | 51781-21-6 | 99.8% | 328.83 | 25 MG
Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma. For research use only. We do not sell to patients. Carteolol HCl is a beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
- Significantly inhibited H2O2-induced cell damage at 1 mmol/L (P<0.05) and scavenged O2 (EC50 value: 48 mmol/L).
- Exhibits protective action against UVB-induced HCEC damage, possibly due to its radical scavenging ability.
- A new alginate formulation of long-acting carteolol 1% given once daily is as effective as standard 1% carteolol given twice daily for glaucoma treatment, with comparable safety.
Medchemexpress LLC Lycorine Hydrochloride Monohydrate | 6150-58-9 | 99.2% | 341.79 | 100 MG
Lycorine Hydrochloride Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent.
- Can be used as a biological material.
- Can be used as an organic compound for life science related research.
Medchemexpress LLC PD 128907 hydrochloride | 112960-16-4 | 99.5% | 285.77 g/mol | C14H20ClNO3 | 50 MG
PD 128907 hydrochloride is a selective dopamine D3 receptor agonist used as a biochemical reagent for life-science research. It exhibits sub-nanomolar potency at D3 receptors (EC50 ~0.64 nM) and substantial selectivity over D2 receptors, and is supplied as a high-purity solid for in vitro pharmacology and receptor-binding studies.
- Potent D3 receptor agonist with EC50 ~0.64 nM.
- High selectivity over D2 receptors (≈53-fold).
- Reported high purity suitable for research use.
- Available in small package sizes for experimental workflows.
- Applicable to dopaminergic signaling and receptor pharmacology studies.
Chem-Impex International, Inc. 4-Benzyloxyaniline hydrochloride | 51388-20-6 | MFCD00012995 | 25G
4-Benzyloxyaniline hydrochloride, 51388-20-6, MFCD00012995, 25G
Medchemexpress LLC Icotinib hydrochloride | 1204313-51-8 | C22H22ClN3O4 | 10 MM 1 ML
Icotinib Hydrochloride is a potent, CNS-penetrant, and specific Epidermal Growth Factor Receptor (EGFR) inhibitor. It is effective against various mutant forms of EGFR and functions as a click chemistry reagent due to its Alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition with Azide groups. This compound inhibits the proliferation of several cancer cell lines and demonstrates dose-dependent antitumor effects in animal models.
- Potent and specific EGFR inhibitor
- Effective against mutant EGFR forms
- Functions as a click chemistry reagent
- Inhibits kinase activity and tumor cell proliferation
- Exhibits dose-dependent antitumor effects in vivo
- Well-tolerated in animal studies
- Investigated in clinical trials for Non-Small Cell Lung Cancer and other conditions
Medchemexpress LLC Etazolate hydrochloride | 35838-58-5 | MFCD00209848 | 98.0% | 325.79 g·mol⁻¹ | C14H20ClN5O2 | 25 MG
Etazolate hydrochloride is a small-molecule phosphodiesterase-4 (PDE4) inhibitor and GABAA receptor modulator supplied as a hydrochloride salt for research use. It is typically provided as a solid with high purity and is used in pharmacology and neuroscience studies to probe PDE4-mediated signaling and neuroprotective or antidepressant-like effects.
- High purity (98.0%).
- Molecular formula C14H20ClN5O2 and molecular weight 325.79 g·mol⁻¹.
- Available in small-scale packages, including 25 mg, and as a 10 mM solution in DMSO.
- Supplied as a hydrochloride salt in solid form for convenient handling.
- Used to study PDE4 signaling and GABAA receptor modulation in pharmacology and neuroscience research.
Medchemexpress LLC Iso-H7 dihydrochloride | 140663-38-3 | 99.1% | 364.29 | 1 ML
Iso-H7 dihydrochloride is a potent protein kinase inhibitor. It is characterized by its inhibitory activity against PKC and PKA, demonstrating IC50 values of 22 μM and 34 μM, respectively. This compound also plays a role in the negative control of PKA on satellite cell myogenesis.
- Inhibits protein kinase activity
- Effective against PKC with an IC50 of 22 μM
- Effective against PKA with an IC50 of 34 μM
- Exhibits negative control of PKA on satellite cell myogenesis
Medchemexpress LLC Iso-H7 (dihydrochloride) | 140663-38-3 | 99.1% | 364.29 | 10 MG
Iso-H7 dihydrochloride is a protein kinase inhibitor that exhibits IC50 values of 22 and 34 μM for PKC and PKA, respectively. It also acts as a negative control for PKA in satellite cell myogenesis. This product is intended for research use only and is not sold to patients.
- Inhibitor of protein kinase.
- Specifically inhibits PKC with an IC50 of 22 μM and PKA with an IC50 of 34 μM.
- Demonstrates negative control of PKA on satellite cell myogenesis.
Medchemexpress LLC Drp1i27 dihydrochloride | C20H28Cl2N6O | 50 MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1.
- Increases cellular networks of mitochondria in human and mouse fibroblasts.
- Offers protection against simulated ischemia-reperfusion injury.
- Has a binding affinity of 286 μM in SPR assay and a KD value of 190 μM via MST assay.
- Targets Drp1-mediated mitochondrial fission.