Hydrochlorides
Cayman Chemical 1Deoxynojirimycin hydrochlor
An inhibitor of α-glucosidase I and II (IC50s = ~2 µM for both); inhibits virus spread in HIV-infected lymphocyte cultures at 0.4 mM
Medchemexpress LLC RS-127445 hydrochloride | 199864-86-3 | C17H17ClFN3 | 50 MG
RS-127445 hydrochloride is a selective, high-affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. It demonstrates 1000-fold selectivity for this receptor compared to numerous other receptor and ion channel binding sites. It is intended for research use only.
- Selective 5-HT2B receptor antagonist
- High-affinity binding
- Orally bioavailable
- Demonstrates 1000-fold selectivity
- Suitable for research applications
Medchemexpress LLC Acetamide, N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | 893990-34-6 | 99.7% | 342.44 | 25 MG
VU 0240551 is a potent and selective neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM, demonstrating selectivity against NKCC1. It also inhibits hERG and L-type Ca2+ channels. VU 0240551 has been shown to attenuate GABA-induced hyperpolarization of P cells, induce a positive shift in the P cell GABA reversal potential, and enhance P cell synaptic transmission.
- In HEK293 cells, VU 0240551 showed an IC50 of 568 nM for antagonist activity at KCC2.
- It exhibited an IC50 > 50 μM for antagonist activity at NKKC1 in human HEK293 cells.
- VU 0240551 reduces the P cell response to GABA in a concentration-dependent manner.
Abcam Serotonin hydrochloride (5-HT/5-Hydro x ytryptamine), 5-HT receptor agonist, 1G
MW 212.67 Da, Purity >99%. Endogenous 5-HT receptor agonist. Neurotransmitter involved in diverse physiological functions such as mood, appetite, sleep, sex and temperature in addition to modulating cardiovascular function and the gastrointestinal system. Also a 5-HT transporter substrate.
The product is subject to the following: Abcam Restricted Use Statement
![Medchemexpress LLC N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 | C18H20N6O3S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242004.png-250.jpg)
Medchemexpress LLC N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 | C18H20N6O3S2 | 10 MG
VU 0255035 is a selective, competitive antagonist of the M1 muscarinic acetylcholine receptor used in preclinical research on central nervous system disorders. The compound (CAS 1135243-19-4) has molecular formula C18H20N6O3S2 and is supplied as a high-purity research-grade material for in vitro and in vivo pharmacology.
- Selective M1 receptor antagonism for pharmacological and mechanistic studies.
- High chemical purity suitable for analytical and biological assays.
- Available in multiple small-quantity formats for flexibility in dosing and screening.
- Suitable for both in vitro and in vivo experimental applications.
- Stable when stored under recommended conditions for research use.