Hydrochlorides
Sigma Aldrich Fine Chemicals Biosciences Olopatadine hydrochloride >=98% (HPLC) | 140462-76-6 | MFCD00875716 | 50MG
Olopatadine hydrochloride >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 373.87 | 140462-76-6 | MFCD00875716 | 50MG
Abcam Serotonin hydrochloride (5-HT/5-Hydro x ytryptamine), 5-HT receptor agonist, 1G
MW 212.67 Da, Purity >99%. Endogenous 5-HT receptor agonist. Neurotransmitter involved in diverse physiological functions such as mood, appetite, sleep, sex and temperature in addition to modulating cardiovascular function and the gastrointestinal system. Also a 5-HT transporter substrate.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC RS 127445 199864-87-4 5mg
RS 127445 (CAS 199864-87-4) is a highly selective antagonist of the serotonin 5-HT2B receptor displaying nanomolar affinity (pKi 9 5 pIC50 10 4) and approximately 1000-fold selectivity over other receptor subtypes By inhibiting 5-HT2B-mediated signaling RS 127445 suppresses serotonin-induced increases in inositol phosphate and intracellular calcium in cellular models In vivo administration in rat models reduces stress- and TNBS-induced visceral hypersensitivity and attenuates colonic motility responses RS 127445 is widely used to elucidate 5-HT2B receptor functions in neurogastroenterology and mechanisms of gastrointestinal hypersensitivity
Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 25mg
Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
Apexbio Technology LLC RS 127445 199864-87-4 10mg
RS 127445 (CAS 199864-87-4) is a highly selective antagonist of the serotonin 5-HT2B receptor displaying nanomolar affinity (pKi 9 5 pIC50 10 4) and approximately 1000-fold selectivity over other receptor subtypes By inhibiting 5-HT2B-mediated signaling RS 127445 suppresses serotonin-induced increases in inositol phosphate and intracellular calcium in cellular models In vivo administration in rat models reduces stress- and TNBS-induced visceral hypersensitivity and attenuates colonic motility responses RS 127445 is widely used to elucidate 5-HT2B receptor functions in neurogastroenterology and mechanisms of gastrointestinal hypersensitivity
Apexbio Technology LLC Terbinafine HCl 78628-80-5 200mg
Terbinafine hydrochloride (CAS 78628-80-5) is a small-molecule inhibitor targeting squalene epoxidase It is designed to selectively inhibit this key enzyme within the fungal sterol biosynthesis pathway thereby disrupting cell membrane integrity Terbinafine hydrochloride exerts its biological activity primarily through non-competitive inhibition of squalene epoxidase In experimental studies Terbinafine hydrochloride demonstrates potent antifungal activity with reported IC50 values against fungal squalene epoxidase in the nanomolar range Based on these pharmacological properties Terbinafine hydrochloride holds research potential in antifungal drug mechanism studies fungal sterol metabolism and therapeutic strategies against fungal pathogens in experimental models
Selleck Chemical LLC Terbinafine-50mg
Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
Apexbio Technology LLC VU 0364439 1246086-78-1 100mg
VU 0364439 (CAS 1246086-78-1) is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4) a member of the class C G protein-coupled receptor (GPCR) family involved in regulating glutamatergic neurotransmission In vitro studies have demonstrated that VU 0364439 enhances mGluR4 activity with an EC50 of 19 8 nM exhibiting greater maximal response and potency compared to the partially selective PAM ()-PHCCC Although its pharmacokinetic properties limit in vivo applications VU 0364439 serves as a valuable tool compound for investigating mGluR4 function and modulation in cellular assays
Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 5mg
Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
Apexbio Technology LLC Duloxetine HCl 136434-34-9 10mg
Duloxetine hydrochloride (CAS 136434-34-9) is a small molecule compound classified as a selective inhibitor of serotonin and norepinephrine reuptake By blocking the reabsorption of these neurotransmitters at the synaptic cleft duloxetine modulates serotonergic and noradrenergic signaling within the central nervous system This pharmacological action has rendered it a valuable tool in research models investigating neurochemical pathways involved in mood regulation pain perception and stress response Duloxetine HCl is commonly utilized in studies of depression anxiety and chronic pain to elucidate monoaminergic mechanisms and to evaluate therapeutic strategies targeting neurotransmitter reuptake
Apexbio Technology LLC VU 0361737 1161205-04-4 100mg
VU 0361737 (CAS 1161205-04-4) is a selective brain-penetrant positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4) It demonstrates high selectivity for mGluR4 over other mGluR subtypes with EC50 values of 240 nM for human and 110 nM for rat mGluR4 and shows minimal to no activity at mGluR1 mGluR2 mGluR3 mGluR6 and mGluR7 while exhibiting weak activity at mGluR5 and mGluR8 VU 0361737 crosses the blood-brain barrier and achieves significant brain exposure (brain plasma ratio of 4 1) with a short half-life (T1/2 20 min) following administration in rats This compound is utilized in studies exploring the modulation of basal ganglia neurotransmission and the pathophysiology of Parkinson s disease
Apexbio Technology LLC Nitrocaramiphen hydrochloride 98636-73-8 10mg
Nitrocaramiphen hydrochloride (CAS 98636-73-8) is a small molecule that acts as a selective antagonist of muscarinic acetylcholine M1 receptors exhibiting a Ki of 5 5 nM Studies indicate that it effectively inhibits the hyperpolarizing effects induced by muscarinic agonists in muscle fibers Due to its receptor specificity nitrocaramiphen hydrochloride is widely utilized in neurobiological research to investigate cholinergic signaling pathways and the physiological roles of M1 receptor modulation
Chem-Impex International, Inc. O-Benzyl-hydroxylamine hydrochloride | 2687-43-6 | MFCD00012952 | 25G
O-Benzyl-hydroxylamine hydrochloride, 2687-43-6, MFCD00012952, 25G
Chem-Impex International, Inc. O-Benzyl-hydroxylamine hydrochloride | 2687-43-6 | MFCD00012952 | 100G
O-Benzyl-hydroxylamine hydrochloride, 2687-43-6, MFCD00012952, 100G