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PNU-22394 hydrochloride is a research-grade small molecule agonist of serotonin (5-HT) receptors, reported as a 5-HT2C agonist and partial 5-HT2A/2B agonist. Supplied as the hydrochloride salt and provided at high purity for pharmacology and receptor biology studies in vitro and in vivo.
Potent 5-HT2C agonist with reported Ki ≈ 6.1 nM and 5-HT2A activity ≈ 10 nM.
Hydrochloride salt, suitable for dissolution in common assay solvents.
Molecular formula C13H17ClN2 and molecular weight 236.74 g/mol.
High purity (>98.7%), appropriate for research applications.
Intended for pharmacological research and receptor characterization studies.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PNU-22394 hydrochloride is a research-grade small-molecule agonist of serotonin (5-HT) receptors, showing selectivity for 5-HT2C and activity at 5-HT2A. Supplied as a hydrochloride salt, it is intended for in vitro pharmacology and receptor signaling studies.
Selective agonist at 5-HT2C with Ki = 6.1 nM.
Also active at 5-HT2A (Ki = 10 nM).
Assay-dependent EC50: 5-HT2C 7.7 nM (Fluo-4/Ca2+) and 0.12 μM (IP-One); 5-HT2A 23 nM (Fluo-4/Ca2+) and 0.21 μM (IP-One).
Molecular formula C13H17ClN2; molecular weight 236.74 g/mol.
High chemical purity (98.8%).
Available in small milligram quantities for laboratory research.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More