Hydrochlorides

Medchemexpress LLC Biotin-PEG4-picolyl azide | 2222687-71-8 | MFCD29052186 | 98.7% | 622.74 | C27H42N8O7S | 5 MG

Biotin-PEG4-picolyl azide is a biotinylated click-chemistry reagent containing a PEG4 spacer and a picolyl azide moiety. It is designed for copper-catalyzed azide-alkyne cycloaddition (CuAAC) to conjugate biotin to alkyne-containing biomolecules for labeling, enrichment, and detection in chemical biology workflows.

• Picolyl azide enhances copper-catalyzed azide-alkyne cycloaddition kinetics.
• PEG4 spacer improves solubility and provides a flexible linkage.
• Biotin tag enables affinity capture and detection of conjugates.
• High purity suitable for analytical and preparative labeling workflows.
• Small pack size appropriate for milligram-scale reactions.

Medchemexpress LLC Erlotinib (hydrochloride) | 183319-69-9 | 99.9% | 1 G

Erlotinib hydrochloride is the hydrochloride salt of erlotinib, a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase intended for research use. It inhibits purified EGFR kinase with an IC50 of 2 nM and contains an alkyne group enabling copper-catalyzed azide-alkyne cycloaddition (click chemistry).

• Inhibits EGFR kinase; IC50 = 2 nM.
• Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
• High purity (99.94%) suitable for analytical and research applications.
• Molecular formula C22H24ClN3O4, molecular weight 429.90.
• Solid, melting point 223-225 °C; recommended storage 4 °C (sealed).
• Typically supplied as a 1 g research pack.

Medchemexpress LLC Biotin-PEG4-picolyl azide | 2222687-71-8 | MFCD29052186 | 98.7% | C27H42N8O7S | 10MG

Biotin-PEG4-picolyl azide is a biotinylated PEG linker with a picolyl azide group designed for click chemistry and biochemical workflows. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and the biotin moiety enables affinity capture, detection, and purification in assays.

• Enables CuAAC reactions with alkyne-containing molecules.
• Compatible with SPAAC reactions using DBCO or BCN partners.
• Provides a biotin affinity tag for capture and detection workflows.
• PEG4 spacer improves solubility and reduces steric hindrance.
• High purity suitable for biochemical applications.