Organic potassium salts
Medchemexpress LLC Butabindide oxalate 1mg | 185213-03-0 | 1MG
Butabindide (UCL-1397) oxalate is a potent selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 M for TPP II and TPP I respectively Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation[1 [2
Biotium 5, 5'-Dibromo BAPTA, tetrapotassium salt
BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium. Key advantages of these calcium chelators include relative insensitivity toward intracellular pH change and fast release of calcium.Several BAPTA chelators with calcium dissociation constants covering the biologically significant range from 10-7 to 10-2 M are available. Properties: Kd (no Mg2 ): 3.6 uM; White to off-white solid soluble in water; Store at 4°C; C22H18Br2K4N2O10; MW: 786.59; [73630-11-2]
Medchemexpress LLC N,N'-Dinitrosopiperazine | 140-79-4 | 99.9% | 144.13 | 50 MG
N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is identified as a carcinogen that specifically targets the nasopharyngeal epithelium and contributes to nasopharyngeal carcinoma (NPC) metastasis. It influences various signaling pathways through protein phosphorylation, including LYRIC at serine 568.
- Does not inhibit 6-10B cells at lower concentrations (0-8 μm)
- Exhibits cytotoxicity from 10 μm upwards
- Enhances 6-10B cell invasion and motility in a dose-dependent manner (2-8 μm)
- Increases cell invasion by 421.7% and motility by 328.2% at 6 μm
- Upregulates phospho-LYRIC s568 and LYRIC expression in CNE1 cells
- Inhibits cell motility and invasion in vivo at 40 mg/kg
- Facilitates NPC metastasis in vivo at 40 mg/kg
- Shows higher phospho-LYRIC expression in metastatic tumors in DNP-treated mice