Organophosphorus compounds
![Medchemexpress LLC N-(3,5-dimethylphenyl)-N'-[2-(trifluoromethyl)phenyl]-guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 | C16H16F3N3 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242649.png-250.jpg)
Medchemexpress LLC N-(3,5-dimethylphenyl)-N'-[2-(trifluoromethyl)phenyl]-guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 | C16H16F3N3 | 1 ML
1A-116 is a small-molecule Rac1 inhibitor used in biological research to block Rac1 activation and downstream signaling. It disrupts Rac1-P-Rex1 interaction, induces apoptosis, and inhibits cell proliferation, migration, and cell cycle progression, and has shown antimetastatic activity in vivo.
- Potent Rac1 inhibitor that blocks Rac1-P-Rex1 interaction.
- Induces apoptosis and inhibits cell proliferation, migration, and cell cycle progression.
- Demonstrated antimetastatic activity in vivo.
- Available as a 10 mM solution in DMSO (1 mL) and in solid formats.
- High purity, 99.7%.
- Molecular weight 307.31 g/mol and formula C16H16F3N3.
- Recommended storage: powder at -20°C; in solvent at -80°C for long-term storage.
Medchemexpress LLC rno-miR-223-3p antag 20nmol | 20nmol
rno-miR-223-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA antagomirs have 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 1 cholesterol group at the 3 end and full-length nucleotide 2 -methoxy modification The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors they exhibits enhanced cellular uptake stability and regulatory activity in vivo
Apexbio Technology LLC LEP (116-130) (mouse) 258276-95-8 25mg
LEP 116-130 (mouse) is an amidated peptide fragment derived from mouse leptin It is designed to mimic leptin-like biological activities thereby contributing to the regulation of energy balance and appetite through hypothalamic signaling pathways LEP 116-130 (mouse) exerts its biological activity by engaging pathways associated with body weight homeostasis and food consumption Based on these pharmacological properties LEP 116-130 (mouse) holds research potential in the fields of obesity metabolism regulation and related signaling pathologies
Medchemexpress LLC hsa-miR-302d-3p agom 5nmol | 5nmol
hsa-miR-302d-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 3 end cholesterol group and full-length nucleotide 2 -methoxy modification They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies Compared with miRNA mimics they exhibits enhanced cellular uptake stability and regulatory activity in vivo
Medchemexpress LLC YKL-1-116 5mg | 1957202-71-9 | 606.72 | C34H38N8O3 | 5 MG
YKL-1-116 is a selective, covalent inhibitor of cyclin-dependent kinase 7 (CDK7) used in laboratory research to probe CDK7-dependent cell cycle and transcriptional processes. It is more potent than related inhibitors against CDK7 and shows limited activity against CDK9, CDK12, and CDK13. Supplied as a small, high-purity solid for research use only (not for human consumption).
- Selective covalent inhibitor of CDK7.
- Higher potency against CDK7 compared with related compounds.
- Minimal activity against CDK9, CDK12, and CDK13.
- High reported purity (~98.7%).
- Provided as a small solid quantity suitable for in vitro research.
- Molecular weight 606.72 and formula C34H38N8O3.
Medchemexpress LLC hsa-miR-195-3p inhib 5nmol | 5nmol
hsa-miR-195-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA inhibitors have full-length nucleotide 2 -methoxy modification The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning
Medchemexpress LLC LEP(116-130)(mouse) | 258276-95-8 | 99.2% | 1560.73 | 5 MG
LEP(116-130)(mouse) is a synthetic leptin peptide fragment intended for research use only. It has been shown to reduce body weight gain and blood glucose levels in vivo.
- Unable to inhibit AP-OB binding in vitro
- Reduces rate of body weight gain in vivo despite increased food intake
- Significantly reduces blood glucose levels by approximately 100 mg/dL in vivo
- No effect on the ability to thermoregulate in wild-type mice
