Organophosphorus compounds
Medchemexpress LLC Gamitrinib TPP hexafluorophosphate | 1131626-47-5 | 99.7% | 1036.03 | C52H65F6N3O8P2 | 10 MG
Gamitrinib TPP hexafluorophosphate is a mitochondria-targeted HSP90 inhibitor that selectively accumulates in the mitochondrial matrix and disrupts mitochondrial Hsp90 function. It is used in biochemical and cell-based cancer research to induce mitochondrial dysfunction and mitophagy and to probe mitochondrial protein homeostasis. The compound is supplied as a high-purity, pale purple solid suitable for in vitro studies.
- Selectively targets mitochondria via a triphenylphosphonium moiety.
- Inhibits mitochondrial HSP90 ATPase activity to disrupt protein folding.
- Demonstrates anticancer activity in cell-based models.
- High purity suitable for research applications.
- Soluble in DMSO; insoluble in water.
- Stable when stored under recommended low-temperature conditions.
Strem, An Ascensus Company CAS# 3115-68-2. 100g. Tetra-n-butylphosphonium bromide, 98%. MFCD00011853
CAS# 3115-68-2. 100g. Tetra-n-butylphosphonium bromide, 98%. MFCD00011853. Molecular Weight: 339.35. Molecular Formula: (C4H9)4P+Brae. Color/form: white xtl. Strem# 93-1579. http://www.strem.com/catalog/v/93-1579/
Strem, An Ascensus Company CAS . 50g. Trihexyl(tetradecyl)phosphonium dicyanamide min. 93% CYPHOS IL 105. MFCD04117699
50g. Trihexyl(tetradecyl)phosphonium dicyanamide min. 93% CYPHOS IL 105. MFCD04117699. Molecular Weight 550.91. Molecular Formula [(C6H13)3(C14H29)P][NCNHCN]ae. Color/form pale yellow liq. Strem 15-6390. http//www.strem.com/catalog/v/15-6390/
eMolecules (S)-Methyl-morpholin-3-ylmethyl-amine dihydrochloride | 2305080-44-6 | | 1g
J & W PharmLab LLC | (S)-Methyl-morpholin-3-ylmethyl-amine dihydrochloride | 1g | 448727153 | 53R0272S | 97.000 | 2305080-44-6 | | 203.110 | C6H16Cl2N2O
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Strem, An Ascensus Company CAS# 28240-69-9. 2g. 1,2-Bis(dichlorophosphino)ethane, min. 97%. MFCD00009609
CAS# 28240-69-9. 2g. 1,2-Bis(dichlorophosphino)ethane, min. 97%. MFCD00009609. Molecular Weight: 231.81. Molecular Formula: Cl2PCH2CH2PCl2. Color/form: colorless to pale yellow liq. Strem# 15-0082. http://www.strem.com/catalog/v/15-0082/
Medchemexpress LLC EMU-116 | 2241724-59-2 | 98.5% | 405.58 | 100 MG
EMU-116 is an orally active CXCR4 antagonist. It can be used in the study of cancer.
- Orally active CXCR4 antagonist.
- Used in the study of cancer.
Medchemexpress LLC Triethyl phosphonoacetate | 867-13-0 | MFCD00009177 | 99.8% | 224.19 g/mol | C8H17O5P | 100g
Carbethoxymethyldiethyl phosphonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Achra(97-116) | 663154-30-1 | 99.4% | 2252.56 | 1 MG
AChRα(97-116) is a synthetic peptide corresponding to the 97-116 region of the rat acetylcholine receptor α-subunit, and also an inducer of autoimmune diseases. It can be used in studies related to experimental autoimmune myasthenia gravis.
- Does not induce significant proliferation of lymphocytes.
- Maintains antigen-specific immune cell phenotype responsive to dopaminergic modulation.
- Effectively detects elevated antibody levels in serum.
- Stimulates T cells to differentiate into Tfh cells.
- Stimulates lymph node-derived mononuclear cells to produce elevated percentages of pre-Tfh cells.
- Induces experimental autoimmune myasthenia gravis in Lewis rats.
- Drives elevated antibody production, reduced muscle clusters, and expansion of Tfh cells.
Medchemexpress LLC mmu-miR-378a-3p inhi 20nmol | 20nmol
mmu-miR-378a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA inhibitors have full-length nucleotide 2 -methoxy modification The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning