Organophosphorus compounds
Medchemexpress LLC EMU-116 | 2241724-59-2 | 98.5% | 405.58 | 1 ML
EMU-116 is an orally active CXCR4 antagonist. EMU-116 can be used in the study of cancer. For research use only. We do not sell to patients.
- Orally active CXCR4 antagonist
- Can be used in the study of cancer
Medchemexpress LLC hsa-miR-296-3p agomi 20nmol | 20nmol
hsa-miR-296-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 3 end cholesterol group and full-length nucleotide 2 -methoxy modification They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies Compared with miRNA mimics they exhibits enhanced cellular uptake stability and regulatory activity in vivo
Medchemexpress LLC AChRα(97-116) TFA | 98.1% | 2252.56 | 1 MG
AChRα(97-116) TFA is a peptide that can induce experimental autoimmune myasthenia gravis (EAMG). This product is for research use only.
- High purity of 98.12%
- Molecular weight: 2252.56 (free acid)
- Appearance: White solid
- Sequence: Asp-Gly-Asp-Phe-Ala-Ile-Val-Lys-Phe-Thr-Lys-Val-Leu-Leu-Asp-Tyr-Thr-Gly-His-Ile
- Acts as an inhibitor of nicotinic acetylcholine receptors (nAChR)
- Soluble in DMSO and specific aqueous formulations
![Medchemexpress LLC N-(3,5-dimethylphenyl)-N'-[2-(trifluoromethyl)phenyl]-guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 | C16H16F3N3 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242649.png-250.jpg)
Medchemexpress LLC N-(3,5-dimethylphenyl)-N'-[2-(trifluoromethyl)phenyl]-guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 | C16H16F3N3 | 1 ML
1A-116 is a small-molecule Rac1 inhibitor used in biological research to block Rac1 activation and downstream signaling. It disrupts Rac1-P-Rex1 interaction, induces apoptosis, and inhibits cell proliferation, migration, and cell cycle progression, and has shown antimetastatic activity in vivo.
- Potent Rac1 inhibitor that blocks Rac1-P-Rex1 interaction.
- Induces apoptosis and inhibits cell proliferation, migration, and cell cycle progression.
- Demonstrated antimetastatic activity in vivo.
- Available as a 10 mM solution in DMSO (1 mL) and in solid formats.
- High purity, 99.7%.
- Molecular weight 307.31 g/mol and formula C16H16F3N3.
- Recommended storage: powder at -20°C; in solvent at -80°C for long-term storage.
Strem, An Ascensus Company CAS# 122-52-1. 1kg. Triethylphosphite, 98%. MFCD00009084
CAS# 122-52-1. 1kg. Triethylphosphite, 98%. MFCD00009084. Molecular Weight: 166.16. Molecular Formula: (C2H5O)3P. Color/form: colorless liq. Strem# 15-6350. http://www.strem.com/catalog/v/15-6350/
Medchemexpress LLC hsa-miR-185-3p mimic 5nmol | 5nmol
hsa-miR-185-3p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
Medchemexpress LLC hsa-miR-302d-3p agom 20nmol | 20nmol
hsa-miR-302d-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 3 end cholesterol group and full-length nucleotide 2 -methoxy modification They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies Compared with miRNA mimics they exhibits enhanced cellular uptake stability and regulatory activity in vivo
Medchemexpress LLC Triethyl phosphonoacetate | 867-13-0 | MFCD00009177 | 99.8% | 224.19 g/mol | C8H17O5P | 25g
Carbethoxymethyldiethyl phosphonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Trimethylolpropane ethoxylate triacrylate | 28961-43-5 | 428.47 | 50 G
Trimethylolpropane ethoxylate triacrylate is an acrylate monomer with multiple acrylate functional groups, used for polymerization and cross-linking reactions. It is widely used in the preparation of curing resins for 3D printing, optical coatings for display devices, and dental composite restorations.
- Acrylate monomer
- Features multiple acrylate functional groups
- Used for polymerization reactions
- Used for cross-linking reactions
- Widely used in the preparation of curing resins for 3D printing
- Used in optical coatings for display devices
- Used in dental composite restorations
Medchemexpress LLC Trimethylolpropane ethoxylate triacrylate | 28961-43-5 | 428.47 | 100 G
Trimethylolpropane ethoxylate triacrylate (ETPTA) is a plasticizer that can be used to synthesize nanocomposites. It is intended for research use only.
- Used as a plasticizer for synthesizing nanocomposites.
- Suitable for laboratory chemical applications.
- Appears as a colorless to light yellow liquid.
- Soluble in DMSO (≥ 100 mg/mL).
- Store at 4°C, protected from light.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- Ships at room temperature if less than 2 weeks.
- Can be used in fabricating photonic crystals.
Medchemexpress LLC Trimethylolpropane ethoxylate triacrylate | 28961-43-5 | 428.47 | 25 G
Trimethylolpropane ethoxylate triacrylate (ETPTA) is a plasticizer. It can be used to synthesize nanocomposites and has applications in the fabrication of photonic crystals.
- Can be used to synthesize nanocomposites.
- Utilized in the fabrication of photonic crystals with different positions of the photonic stop band.
- Enables inversion of opal-type templates using photopolymerization of an ETPTA photocurable resin.
- Facilitates embedding of gold nanoparticles into inverse ETPTA films by multiple infiltration.
Medchemexpress LLC DGY-06-116 | 2556836-50-9 | 98.6% | 597.11 | 1 ML
DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. It also demonstrates inhibitory activity against FGFR1. This compound exhibits potent antiproliferative effects in various cancer cell lines, including nonsmall cell lung cancer (NSCLC) and triple negative breast cancer (TNBC), by inhibiting SRC signaling.
- Potent and selective Src inhibitor (IC50: 3 nM)
- Irreversible covalent mechanism
- Inhibits Src kinase activity with an IC50 of 2.6 nM at 1 hour incubation
- Demonstrates antiproliferative effects in H1975, HCC827, and MDA-MB-231 cell lines
- Induces potent SRC binding and inhibition of SRC signaling
- Inhibits p-SRCY416 signaling in NSCLC cells
- Exhibits in vivo efficacy in adult C57B6 mice, inhibiting SRC for an extended duration
![Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243461.png-250.jpg)
Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 50 MG
1A-116 is a small-molecule Rac1 inhibitor for research use that blocks Rac1 activation and disrupts Rac1-P-Rex1 interaction. It prevents EGF-induced Rac1 activation and has been shown to induce apoptosis in a circadian-dependent manner. Supplied as a white to off-white solid, the compound has a molecular weight of 307.31 g·mol⁻¹ and high purity (~99.7%), appropriate for biochemical and cell-based studies.
- Blocks Rac1 activation and Rac1-P-Rex1 interaction.
- Prevents EGF-induced Rac1 activation in cell assays.
- Induces apoptosis in a circadian-dependent manner in studied models.
- High purity suitable for biochemical and cell-based experiments.
- Available in multiple small-scale packaging options for laboratory research.
- Stable as a powder under recommended storage conditions.
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.5% | 368.46 g/mol | C18H20N6OS | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240040.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.5% | 368.46 g/mol | C18H20N6OS | 5 MG
CYC-116 is a small-molecule research compound that selectively inhibits Aurora kinases A and B. It is used to probe cell cycle regulation and anticancer mechanisms in biochemical and cellular assays, and is supplied in solid and solution formats for laboratory use.
- Potent inhibition of Aurora A and B (Ki ≈ 8 nM and 9.2 nM).
- Suitable for biochemical and cellular assays.
- Available as solid and as DMSO solution for convenient dosing.
- Molecular weight 368.46 g/mol; molecular formula C18H20N6OS.
- High reported purity (≈99.5%) for research applications.
Medchemexpress LLC hsa-miR-302d-3p agom 5nmol | 5nmol
hsa-miR-302d-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 3 end cholesterol group and full-length nucleotide 2 -methoxy modification They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies Compared with miRNA mimics they exhibits enhanced cellular uptake stability and regulatory activity in vivo