Sulfonyl halides
Medchemexpress LLC Calmidazolium chloride | 57265-65-3 | MFCD00077679 | 99.9% | 687.70 g/mol | C31H23Cl7N2O | 1 ML
Calmidazolium chloride is a calmodulin antagonist used in biochemical and cellular research to inhibit calmodulin-dependent enzymes and calcium-transport processes. Supplied as a 10 mM solution (1 mL), it is suitable as a research reagent for signaling, enzymology, and cellular assays.
- High purity (approximately 99.9%).
- Molecular formula C31H23Cl7N2O.
- Molecular weight 687.70 g/mol.
- CAS number 57265-65-3.
- Calmodulin antagonist with reported Kd of 3 nM.
- Provided as a small-volume, ready-to-use stock solution for experimental convenience.
Medchemexpress LLC Trigonelline chloride | 6138-41-6 | 173.60 | 500 MG
Trigonelline chloride is an alkaloid isolated from *Trigonella foenum-graecum L* or *Leonurus artemisia*. It possesses potential antidiabetic activity and acts as a potent Nrf2 inhibitor, blocking Nrf2-dependent proteasome activity to enhance apoptosis in pancreatic cancer cells. It also demonstrates anti-HSV-1, antibacterial, and antifungal activities, and induces ferroptosis.
- Alkaloid with potential antidiabetic activity.
- Potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity.
- Enhances apoptosis in pancreatic cancer cells.
- Possesses anti-HSV-1, antibacterial, and antifungal activity.
- Induces ferroptosis.
Aobchem 2-(2-Methyl-1 3-dioxolan-2-yl)thiazole-5-carboxylic acid | ≥97% | CAS 1909309-55-2 | C8H9NO4S | 1g
2-(2-Methyl-1 3-dioxolan-2-yl)thiazole-5-carboxylic acid | ≥97% | CAS 1909309-55-2 | C8H9NO4S | 1g
Aobchem 3-Methyl-N-(phenylmethyl)benzenesulfonamide | 95% | CAS 321704-25-0 | C14H15NO2S | 1g
3-Methyl-N-(phenylmethyl)benzenesulfonamide | 95% | CAS 321704-25-0 | C14H15NO2S | 1g
Aobchem 3-(1 3-Dioxolan-2-yl)-2-fluorobenzaldehyde | 97% | CAS 2901084-97-5 | C10H9FO3 | 1g
3-(1 3-Dioxolan-2-yl)-2-fluorobenzaldehyde | 97% | CAS 2901084-97-5 | C10H9FO3 | 1g
Medchemexpress LLC Amg-1694 | 1361217-07-3 | 533.63 | 25 MG
AMG-1694 is a potent glucokinase-glucokinase regulatory protein (GK-GKRP) disruptor. It promotes the dissociation of the GK-GKRP complex with an IC50 of 7 nM, thereby indirectly increasing GK enzymatic activity. It effectively reverses the inhibitory effect of GKRP on GK activity and encourages GK translocation. In various rodent models of diabetes, AMG-1694 normalizes blood glucose levels, with its effect restricted to diabetic animals and not observed in normoglycemic ones.
- IC50 & target: 7 nM (GK-GKRP)
- Hepatocyte EC50: 0.082 μM (inhibition of GKRP-GK interaction in rat primary hepatocytes)
- Hepatocyte EC50: 1.79 μM (induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes)
- In vitro: Effectively restores the enzymatic activity of GK with an EC50 of 0.020 μM in the presence of GKRP
Aobchem 2-Fluoro-5-(methanesulfonyl)benzoic acid | ≥95% | CAS 247569-56-8 | C8H7FO4S | 1g
2-Fluoro-5-(methanesulfonyl)benzoic acid | ≥95% | CAS 247569-56-8 | C8H7FO4S | 1g
Aobchem 4-(1 3-Dioxolan-2-yl)benzonitrile | ≥97% | CAS 66739-89-7 | C10H9NO2 | 1g
4-(1 3-Dioxolan-2-yl)benzonitrile | ≥97% | CAS 66739-89-7 | C10H9NO2 | 1g
eMolecules 76543-27-6 | 1-(4-methylbenzenesulfonyl)azetidin-3-one | MFCD00129860 | 25g
Pharmablock | 1-(4-methylbenzenesulfonyl)azetidin-3-one | 25g | 551271616 | PBN20121417 | 76543-27-6 | MFCD00129860 | 225.260 | C10H11NO3S
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Chem-Impex International, Inc. 3-Chloropropanesulphonyl chloride | MFCD00007463 | 25G
3-Chloropropanesulphonyl chloride, MFCD00007463, 25G
Matrix Scientific 3-CYANO-4-FLUOROBENZENESULF-5G
3-Cyano-4-fluorobenzenesulfonyl chloride, 5g,C7H3ClFNO2S, MFCD03093760, mw 219.62, [351003-23-1]
Matrix Scientific 2,4,6-TRICHLOROBENZENESULFO-5G
2,4,6-Trichlorobenzenesulfonyl chloride, 98%; 5g,C6H2Cl4O2S, MFCD00052973, mw 279.96, [51527-73-2]
Medchemexpress LLC Taplucainium chloride | 2489565-37-7 | 98.0% | 386.96 | C23H31ClN2O | 10 MG
Taplucainium chloride is a small-molecule sodium channel blocker intended for laboratory research. It exhibits 70-95% inhibition of sodium channel activity at 10 μM and is reported to have analgesic potential. The compound is supplied as an off-white to light-yellow solid with a reported purity of 98.0% and is available as a solid or solution for experimental use.
- Small-molecule sodium channel blocker with demonstrated activity (70-95% inhibition at 10 μM).
- Reported purity of 98.0%.
- Available as a solid and as a 10 mM solution in DMSO for convenience.
- Off-white to light yellow solid appearance suitable for research applications.
- Recommended storage: powder at -20 °C; solutions at -80 °C (6 months) or -20 °C (1 month).
- For research use only; not for clinical or human use.