Vinyl halides
Medchemexpress LLC Flucloxacillin sodium | 1847-24-1 | 98.0% | C19H16ClFN3NaO5S | 1 G
Flucloxacillin sodium is an active antibiotic that effectively targets both gram-positive and gram-negative bacteria. With a purity of 98.02%, it is commonly used in research and has shown efficacy in reducing germs in biofilm and bone tissue in periprosthetic infections. This compound is also being investigated in various clinical trials for conditions such as cellulitis, wound infection, and osteomyelitis.
- Active against gram-positive and gram-negative bacteria
- Effective in periprosthetic infection models
- Reduces germs in biofilm and bone tissue
- Purity of 98.02%
- Soluble in water and DMSO
- Involved in clinical trials for various bacterial infections
Cayman Chemical DmyoInositol1phosphate sodiu
A synthetic, pure phosphoinositol for signal transduction research; can be formed by PLC hydrolysis of phosphatidylinositol or by dephosphorylation of polyphosphate inositols such as Ins(1,3)P2 by inositol polyphosphate 3-phosphatase
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 5 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective, and potent CK2 inhibitor (IC50 values of 1 nM against CK2α and CK2α'). It induces cell-cycle arrest and selectively causes apoptosis in cancer cells, attenuates PI3K/Akt signaling, and demonstrates antiproliferative activity correlating with CK2α catalytic subunit expression. It also prevents leukemic cells from engaging a functional UPR to buffer proteotoxic stress and decreases pro-survival ER chaperon BIP/Grp78 expression.
- Causes cell-cycle arrest
- Induces apoptosis in cancer cells
- Attenuates PI3K/Akt signaling
- Exhibits antiproliferative activity
- Prevents leukemic cells from engaging a functional UPR
- Decreases pro-survival ER chaperon BIP/Grp78 expression
- Induces cytotoxicity
- Suppresses CK2-mediated PI3K/Akt/mTOR signaling pathways
- Demonstrates robust antitumor activity in murine xenograft models
Cayman Chemical DmyoInositol1phosphate sodiu
A synthetic, pure phosphoinositol for signal transduction research; can be formed by PLC hydrolysis of phosphatidylinositol or by dephosphorylation of polyphosphate inositols such as Ins(1,3)P2 by inositol polyphosphate 3-phosphatase
Medchemexpress LLC Trans-2-butene-1,4-dicarboxylic acid | 4436-74-2 | 99.17% | 100 MG
Trans-2-butene-1,4-dicarboxylic acid is an endogenous metabolite. It is for research use only and not sold to patients. It is also described as a metabolite for organic acidurias that can be found in urine.
- Endogenous metabolite
- Metabolite for organic acidurias
- Found in urine
- White to off-white solid
- Chemical formula: C6H8O4
- Molecular weight: 144.13
- Classified as ketone, aldehyde, and acid
Medchemexpress LLC Inclisiran sodium, sense strand | 00-00-0 | 97.4% | 10MG
SS-Inclisiran (sodium) is the sense strand component of inclisiran, a chemically synthesized small interfering RNA (siRNA) designed to reduce PCSK9 expression by targeting PCSK9 mRNA. Supplied as the sodium salt for laboratory research, it is intended for use in molecular biology studies of lipid regulation and gene silencing.
- Sense strand of an siRNA targeting PCSK9.
- Sodium salt form suitable for research applications.
- Reported purity approximately 97.4%.
- Available in multiple mass sizes for experimental flexibility.
- Intended for research use only, not for therapeutic use.
Medchemexpress LLC Ponceau 4R (Acid Red 18; New Coccine) | 2611-82-7 | 85.0% | 5 G
Ponceau 4R (85%) is a synthetic strawberry red azo dye used as a food coloring. It is synthesized from aromatic hydrocarbons and is stable to light, heat, and acid, but fades in the presence of ascorbic acid. It is intended for research use only.
- Synthetic colorant that may be used as a food coloring.
- Strawberry red azo dye.
- Stable to light, heat, and acid (fades in the presence of ascorbic acid).
Matrix Scientific 3-Fluorophthalic anhydride, 652-39-1, MFCD00039696, 5g
Molecular Formula C8H3FO3,Purity 97%, Molecular Weight 166.11, Melting Point 157-160°
Medchemexpress LLC Benzo[c]-2,6-naphthyridine-8-carboxylic acid, 5-[(3-chlorophenyl)amino]-, sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 1 ML
Silmitasertib sodium salt is an orally bioavailable, highly selective, and potent CK2 inhibitor with IC50 values of 1 nM against CK2α and CK2α'. It exhibits potent anti-cancer activity.
- Orally bioavailable and potent CK2 inhibitor
- Highly selective for CK2α and CK2α'
- Causes cell-cycle arrest and induces apoptosis in cancer cells
- Attenuates PI3K/Akt signaling
- Demonstrates robust antitumor activity in murine xenograft models
- Suitable for research use only
Medchemexpress LLC N-Caproicacid sodiu 100g
N-caproicacid sodium is an anionic surfactant sodium n-caproic acid
Cayman Chemical DmyoInositol3phosphate sodiu
Synthetic, pure phosphoinositol for signal transduction research; can be formed by the dephosphorylation of polyphosphate inositols such as Ins(3,4)P2 by inositol polyphosphate 4-phosphatase
Medchemexpress LLC Adenosine, 8-bromo-, cyclic 3',5'-[hydrogen P(S)]-phosphorothioate], sodium salt (1:1) | 1573115-90-8 | 99.9% | 446.15 | 500 UG
Sp-8-Br-cAMPS sodium is a cAMP analog that activates protein kinase A (PKA). It is known to inhibit T-cell proliferation and the haemocyte non-self response in Lepidoptera larvae. This compound also inhibits phagocytosis of certain bacteria and modulates cytokine expression.
- Activates protein kinase A (PKA) with an EC50 of 360 nM
- Inhibits T-cell proliferation
- Inhibits haemocyte non-self response in Lepidoptera larvae
- Inhibits phagocytosis of *X. nematophila* and *B. subtilis*
- Modulates cytokine expression (IFN-γ, TNF-α, IL-2, IL-4)
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 100 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor.
- Causes cell-cycle arrest and selectively induces apoptosis in cancer cells by attenuating PI3K/Akt signaling.
- Antiproliferative activity correlates with CK2α catalytic subunit expression.
- Prevents leukemic cells from engaging UPR during PS-341 treatment, reducing BIP/Grp78 expression.
- Induces cytotoxicity and apoptosis, exerting anti-proliferative effects in hematological tumors.
- Demonstrates robust antitumor activity and reduces phospho-p21 (T145) in murine xenograft models.