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Metal alkyl halides contain M-X, M-H, and M-R bonds where M is a metal, X is Cl, Br, or I, and R is an alkyl group. Available in various chemical compositions, they are strong reducing agents that react rapidly with oxygen and oxidizing agents.
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This compound is a research-grade small-molecule inhibitor of aldo-keto reductase 1C3 (AKR1C3) that selectively blocks AKR1C3-mediated reduction of doxorubicin and can reverse doxorubicin resistance in AKR1C3-overexpressing cells. Supplied as a high-purity solid, it is intended for biochemical and cellular research applications.
Target: AKR1C3 inhibitor.
Mechanism: selectively blocks AKR1C3-mediated reduction of doxorubicin.
Purity: 99.5% (reported value).
Physical form: white to off-white solid.
Solubility: soluble in DMSO (≈100 mg/mL); in vivo formulations reported in DMSO/corn oil.
Storage: powder stable at -20°C for long-term storage; solutions require low-temperature storage.
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Dodecanedioyl dichloride is the acid chloride derivative of dodecanedioic acid supplied as a reagent for organic synthesis and biochemical assays. It is used as an acylation reagent and as an intermediate in the preparation of diacyl compounds, polymers, and related derivatives.
Acid chloride reagent for acylation reactions and intermediate synthesis.
Molecular weight 267.19 g/mol; formula C12H20Cl2O2.
Appearance: colorless to light yellow liquid.
Purity >98.0% (as listed by distributors).
Density ~1.069 g/cm3.
Suitable for organic synthesis and polymer/intermediate preparation.
Storage: pure form -20°C (up to 3 years) or 4°C (up to 2 years); in solvent, store colder.
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