Organo-Metalloid Compounds
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Filtered Search Results
eMolecules 756526-03-1 | Bis-PEG5-NHS ester | Broadpharm | MFCD11041118 | 532.499 | C22H32N2O13 | 98.000 | O=C(CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1g | 112541631
Bis-PEG5-NHS ester | Broadpharm | 756526-03-1 | MFCD11041118 | 532.499 | C22H32N2O13 | 98.000 | O=C(CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1g | 112541631
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Medchemexpress LLC Bromoacetamido-PEG3-C2-Boc | 1807537-33-2 | C15H28BrNO6 | 250 MG
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Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are composed of two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein. PROTACs work by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Available in various quantities
- Appears as a colorless to light yellow liquid
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Medchemexpress LLC NH2-PEG3-C6-Cl | 1261350-60-0 | 267.79 | 50 MG
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NH2-PEG3-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- One is a ligand for an E3 ubiquitin ligase
- The other is for the target protein
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eMolecules 77544-68-4 | Tos-PEG3 | Medchem Express | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 250mg | 746319413
Tos-PEG3 | Medchem Express | 77544-68-4 | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 250mg | 746319413
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eMolecules 139115-92-7 | BocNH-PEG3-OH | Acrotein ChemBio Inc. | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 5g | 570928212
BocNH-PEG3-OH | Acrotein ChemBio Inc. | 139115-92-7 | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 5g | 570928212
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Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 50 MG
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Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Biotin-PEG3-C3-NH2 | 183896-00-6 | 97.0% | C20H38N4O5S | 50 MG
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Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker with an NH2 functional group, primarily used in the synthesis of PROTACs. This substance is intended for research use only, as a laboratory chemical for the manufacture of other substances.
- PEG-based PROTAC linker with an NH2 functional group
- Used in the synthesis of PROTACs
- Displays fluorescence under streptavidin probes when combined with protein G
- Can be used for high-throughput analysis of protein-small molecule interactions
- Profiles enzyme activities in microarrays constructed by surface derivatization method
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 250 MG
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Aminooxy-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand with a target protein ligand. This product is strictly for research use only and not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ph-PEG3 1g
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Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 1 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC DNP-PEG3-azide | 951671-87-7 | 99.2% | C14H20N6O7 | 500 MG
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DNP-PEG3-azide is a PEG-based PROTAC linker that functions as a click chemistry reagent due to its Azide group. It is utilized in the synthesis of PROTACs, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Reacts with alkyne-containing molecules
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Reacts with molecules possessing DBCO or BCN groups
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Medchemexpress LLC Boc-NH-PEG5-CH2CH2COOH | 1347750-78-0 | MFCD24539478 | ≥97.0% | 409.47 g/mol | C18H35NO9 | 250 MG
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Boc-NH-PEG5-CH2CH2COOH is a Boc-protected PEG5 linker terminating in a propionic acid functionality. It is used as a modular building block for assembling bifunctional molecules such as PROTACs, providing a hydrophilic, flexible spacer and a protected amine handle for selective deprotection and subsequent coupling reactions.
- Hydrophilic PEG5 spacer improves solubility and flexibility.
- Boc-protected amine allows controlled deprotection and functionalization.
- Terminal carboxylic acid enables straightforward coupling to ligands or linkers.
- Moderate molecular weight suitable for linker design without excessive bulk.
- Intended for use as a chemical building block in medicinal chemistry workflows.
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Medchemexpress LLC Azido-PEG3-propionic acid tert-butyl ester | 252881-73-5 | MFCD22201543 | ≥98.0% | 303.35 g/mol | C13H25N3O5 | 100 MG
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Azido-PEG3-propionic acid tert-butyl ester is an azide-functionalized, Boc-protected PEG3 linker for bioconjugation. It acts as a cleavable three-unit PEG spacer and an azide reagent for click chemistry, suitable for assembling antibody-drug conjugates and PROTACs.
- Azide-functionalized Boc-protected PEG3 linker.
- Cleavable three-unit PEG spacer for ADC and PROTAC synthesis.
- Suitable for CuAAC and SPAAC click chemistry.
- Purity ≥98.0%.
- Molecular weight 303.35 g/mol; formula C13H25N3O5.
- Appearance colorless to light yellow liquid; follow storage recommendations.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | ≥97.0% | 263.29 | C10H21N3O5 | 10 G
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Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker bearing a terminal azide and a terminal hydroxyl group. It functions as a non-cleavable, five-unit PEG spacer for bioconjugation and click chemistry applications.
- Contains azide (-N3) and terminal alcohol (-OH) functional groups.
- Water-soluble PEG linker suitable for click chemistry and PROTAC/ADC assembly.
- Molecular weight ~263.29 g/mol; formula C10H21N3O5.
- High purity, typically ≥97.0% by manufacturer specification.
- Available in multiple pack sizes, including 10 g.
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 hydrochloride | 2446474-09-3 | 96.6% | 100 MG
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Pomalidomide-PEG3-C2-NH2 hydrochloride is an E3 ligase ligand and linker conjugate. It is utilized in PROTAC technology for designing and developing novel targeted inhibitors. The E3 ligase ligand component, such as Pomalidomide, binds to a specific E3 ligase, while a linker connects it to a ligand that recognizes a targeted protein, a mechanism crucial for PROTAC activity.
- Functions as an E3 ligase ligand for Cereblon.
- Used in PROTAC technology.
- Aids in designing and developing novel targeted inhibitors.
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